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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1974 Jan 5;110(1):63–66.

Narcolepsy

T J Murray, Anita Foley
PMCID: PMC1947227  PMID: 4809449

Abstract

Narcolepsy is a disorder of sleep control characterized by a tetrad of symptoms: sleep attacks, cataplexy, sleep paralysis and hypnagogic hallucinations. A diagnosis is made from a careful history. The incidence is estimated as high as 0.3% of the population. Unfortunately patients go for many years before the diagnosis is made and often have experienced disruption of their employment, social and family life, and may have experienced a number of car accidents because of falling asleep at the wheel. An unknown number of narcoleptics kill themselves on the highways before the diagnosis is ever made. Sleep attacks can usually be controlled by methylphenidate, and if the other symptoms persist they can often be effectively managed by imipramine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bartels E. C., Kusakcioglu O. Narcolepsy: a possible cause of automobile accidents. Lahey Clin Found Bull. 1965;14(1):21–26. [PubMed] [Google Scholar]
  2. DEMENT W., KLEITMAN N. Cyclic variations in EEG during sleep and their relation to eye movements, body motility, and dreaming. Electroencephalogr Clin Neurophysiol. 1957 Nov;9(4):673–690. doi: 10.1016/0013-4694(57)90088-3. [DOI] [PubMed] [Google Scholar]
  3. Dement W., Rechtschaffen A., Gulevich G. The nature of the narcoleptic sleep attack. Neurology. 1966 Jan;16(1):18–33. doi: 10.1212/wnl.16.1.18. [DOI] [PubMed] [Google Scholar]
  4. Hishikawa Y., Ida H., Nakai K., Kaneko Z. Treatment of narcolepsy with imipramine (tofranil) and desmethylimipramine (pertofran). J Neurol Sci. 1966 Sep-Oct;3(5):453–461. doi: 10.1016/0022-510x(66)90001-3. [DOI] [PubMed] [Google Scholar]
  5. Yoss R. E., Daly D. D. On the treatment of narcolepsy. Med Clin North Am. 1968 Jul;52(4):781–787. [PubMed] [Google Scholar]
  6. Yoss R. E. The sleepy driver: a test to measure ability to maintain alertness. Mayo Clin Proc. 1969 Nov;44(11):769–783. [PubMed] [Google Scholar]

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