Skip to main content

. 1963 Apr;42(4):471–483.

The Response of the Lymphatic Tissue to the Microbial Flora. Studies on Germfree Mice

Heinz Bauer, Richard E Horowitz, Stanley M Levenson, Hans Popper

PMCID: PMC1949649 PMID: 13966929

471

Images in this article

Fig. 1
on p.481

Fig. 2
on p.481

Fig. 3
on p.481

Fig. 4
on p.481

Figs. 5-7
on p.482

Fig. 8
on p.483

Fig. 9
on p.483

Fig. 10
on p.483

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

BARKA T., SCHAFFNER F., POPPER H. Acid phosphatase and reticuloendothelial system. Lab Invest. 1961 May-Jun;10:590–607. [PubMed] [Google Scholar]
BURKHOLDER P. M., LITTELL A. H., KLEIN P. G. Sectioning at room temperature of unfixed tissues, frozen in a gelatin matrix, for immunohistologic procedures. Stain Technol. 1961 Mar;36:89–91. doi: 10.3109/10520296109113250. [DOI] [PubMed] [Google Scholar]
COHEN S., OHTA G., SINGER E. J., POPPER H. Immunocytochemical study of gamma globulin in liver in hepatitis and postnecrotic cirrhosis. J Exp Med. 1960 Feb 1;111:285–294. doi: 10.1084/jem.111.2.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
GMRDON M. A., EDWARDS M. R., TOMPKINS V. N. Refinement of fluorescent antibody by gel filtration. Proc Soc Exp Biol Med. 1962 Jan;109:96–99. doi: 10.3181/00379727-109-27114. [DOI] [PubMed] [Google Scholar]
GORDON H. A. The germ-free animal. Its use in the study of "physiologic" effects of the normal microbial flora on the animal host. Am J Dig Dis. 1960 Oct;5:841–867. doi: 10.1007/BF02232187. [DOI] [PubMed] [Google Scholar]
GUSTAFSSON B. E., LAURELL C. B. G Gamma globulins in germ-free rats. J Exp Med. 1958 Aug 1;108(2):251–258. doi: 10.1084/jem.108.2.251. [DOI] [PMC free article] [PubMed] [Google Scholar]
KORNGOLD L. The distribution and immunochemical properties of human tissue and tumor antigens. Ann N Y Acad Sci. 1957 Dec 16;69(4):681–697. doi: 10.1111/j.1749-6632.1957.tb49709.x. [DOI] [PubMed] [Google Scholar]
LEDUC E. H., COONS A. H., CONNOLLY J. M. Studies on antibody production. II. The primary and secondary responses in the popliteal lymph node of the rabbit. J Exp Med. 1955 Jul 1;102(1):61–72. doi: 10.1084/jem.102.1.61. [DOI] [PMC free article] [PubMed] [Google Scholar]
LEVENSON S. M., MASON R. P., HUBER T. E., MALM O. J., HOROWITZ R. E., EINHEBER A. Germfree animals in surgical research. Ann Surg. 1959 Oct;150:713–730. doi: 10.1097/00000658-195910000-00014. [DOI] [PMC free article] [PubMed] [Google Scholar]
MARSHALL J. D., EVELAND W. C., SMITH C. W. Superiority of fluorescein isothiocyanate (Riggs) for fluorescent-antibody technic with a modification of its application. Proc Soc Exp Biol Med. 1958 Aug-Sep;98(4):898–900. doi: 10.3181/00379727-98-24222. [DOI] [PubMed] [Google Scholar]
MIYAKAWA M. The lymphatic system of germfree guinea pigs. Ann N Y Acad Sci. 1959 May 8;78:221–236. doi: 10.1111/j.1749-6632.1959.tb53105.x. [DOI] [PubMed] [Google Scholar]
ORTEGA L. G., MELLORS R. C. Cellular sites of formation of gamma globulin. J Exp Med. 1957 Nov 1;106(5):627–640. doi: 10.1084/jem.106.5.627. [DOI] [PMC free article] [PubMed] [Google Scholar]
SPRINZ H., KUNDEL D. W., DAMMIN G. J., HOROWITZ R. E., SCHNEIDER H., FORMAL S. B. The response of the germfree guinea pig to oral bacterial challenge with Escherichia coli and Shigella flexneri. Am J Pathol. 1961 Dec;39:681–695. [PMC free article] [PubMed] [Google Scholar]
THORBECKE G. J., BENACERRAF B. Some histological and functional aspects of lymphoid tissue in germfree animals. II. Studies on phagocytosis in vivo. Ann N Y Acad Sci. 1959 May 8;78:247–253. doi: 10.1111/j.1749-6632.1959.tb53107.x. [DOI] [PubMed] [Google Scholar]
THORBECKE G. J., GORDON H. A., WOSTMAN B., WAGNER M., REYNIERS J. A. Lymphoid tissue and serum gamma globulin in young germfree chickens. J Infect Dis. 1957 Nov-Dec;101(3):237–251. doi: 10.1093/infdis/101.3.237. [DOI] [PubMed] [Google Scholar]
THORBECKE G. J., OLD L. J., BENACERRAF B., CLARKE D. A. A histochemical study of acid and alkaline phosphatase in mouse livers during various conditions modifying activity of the reticuloendothelial system. J Histochem Cytochem. 1961 Jul;9:392–399. doi: 10.1177/9.4.392. [DOI] [PubMed] [Google Scholar]
THORBECKE G. J. Some histological and functional aspects of lymphoid tissue in germfree animals. I. Morphological studies. Ann N Y Acad Sci. 1959 May 8;78:237–246. doi: 10.1111/j.1749-6632.1959.tb53106.x. [DOI] [PubMed] [Google Scholar]
TREXLER P. C., REYNOLDS L. I. Flexible film apparatus for the rearing and use of germfree animals. Appl Microbiol. 1957 Nov;5(6):406–412. doi: 10.1128/am.5.6.406-412.1957. [DOI] [PMC free article] [PubMed] [Google Scholar]
TREXLER P. C. The use of plastics in the design of isolator systems. Ann N Y Acad Sci. 1959 May 8;78:29–36. doi: 10.1111/j.1749-6632.1959.tb53093.x. [DOI] [PubMed] [Google Scholar]
VAZQUEZ J. J. Antibody- or gamma globulin--forming cells, as observed by the fluorescent antibody technic. Lab Invest. 1961 Nov-Dec;10:1110–1125. [PubMed] [Google Scholar]
WELSH R. A. Light and electron microscopic correlation of the periodic acid-Schiff reaction in the human plasma cell. Am J Pathol. 1962 Mar;40:285–296. [PMC free article] [PubMed] [Google Scholar]
WOSTMANN B. S. Serum proteins in germfree vertebrates. Ann N Y Acad Sci. 1959 May 8;78:254–260. [PubMed] [Google Scholar]

ACTIONS

PDF (3.1 MB)

RESOURCES