Table 4a.

Predictive value of selected peak cut-offs for determining AI

	Number with AI primary or secondary AI	Number with normal status	Total	Sensitivity %	Specificity %	PPV %	NPV %
Cortisol (μg/dL) used as definition of AI
<20	19	0	19	100	100	100	100
≥20	0	61	61
Total	19	61	80
Aldosterone (ng/dL)
<6	9	10	19	47	84	47	84
≥6	10	51	61
Total	19	61	80
11-deoxycortisol (ng/dL)
<400	16	8	24	84	87	67	95
≥400	3	53	56
Total	19	61	80
DHEA (ng/dL)
<300	18	20	38	95	67	47	98
≥300	1	41	42
Total	19	61	80
Three-steroid profile (aldosterone < 6 ng/dL, 11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL)
Yes	9	0	9	47	100	100	86
No	10	61	71
Total	19	61	80
Two-steroid profile (11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL)
Yes	15	1	16	79	98	94	94
No	4	60	64
Total	19	61	80

PPV = positive predictive value; NPV = negative predictive value