Table 4d.

Predictive value of selected peak cut-offs for determining secondary AI

	Number with secondary AI	Number with normal status	Total	Sensitivity %	Specificity %	PPV %	NPV %
Cortisol (μg/dL) used as definition of AI
<20	12	0	12	100	100	100	100
≥20	0	61	61
Total	12	61	73
Aldosterone (ng/dL)
<6	2	10	12	17	84	17	84
≥6	10	51	61
Total	12	61	73
11-deoxycortisol (ng/dL)
<400	9	8	17	75	87	53	95
≥400	3	53	56
Total	12	61	73
DHEA (ng/dL)
<300	11	20	31	92	67	35	98
≥300	1	41	42
Total	12	61	73
Three-steroid profile (aldosterone ≥ 6 ng/dL, 11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL)
Yes	7	1	8	58	98	88	92
No	5	60	65
Total	12	61	73
Two-steroid profile (11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL)
Yes	8	1	9	67	98	89	94
No	4	60	64
Total	12	61	73

PPV = positive predictive value; NPV = negative predictive value