Skip to main content
NCBI home page
Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1976 May 22;114(10):922–924.

Malabsorption syndrome with IgG(lambda) M component: response to chemotherapy.

E J Prokipchuk, W Pruzanski
PMCID: PMC1957076  PMID: 817794

Abstract

A patient with malabsorption syndrome and steatorrhea was found to have IgG (lambda) M component in the blood and some extracellular deposition of IgG in the intestinal wall. There was no evidence of multiple myeloma. He responded favourably to intermittent courses of melphalan and prednisone.

Full text

PDF
922

Images in this article

923FIG. 1
on p.923
924FIG. 2
on p.924

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beker S., Grases P. J., Merino F., Arends T., Guevara J. Intestinal malabsorption in macroglobulinemia. Am J Dig Dis. 1971 Jul;16(7):648–656. doi: 10.1007/BF02239226. [DOI] [PubMed] [Google Scholar]
  2. Berndt H. Malabsorption in cancer of and outside the bowel. Digestion. 1968;1(5):305–310. doi: 10.1159/000196868. [DOI] [PubMed] [Google Scholar]
  3. Bosseckert H., Winnefeld K., Seidel K. [Macro-amylasaemia with paraproteinemia and the malabsorption syndrome]. Ger Med Mon. 1969 Mar;14(3):133–135. [PubMed] [Google Scholar]
  4. Crabbé P. A., Heremans J. F. Lack of gamma A-immunoglobulin in serum of patients with steatorrhoea. Gut. 1966 Apr;7(2):119–127. doi: 10.1136/gut.7.2.119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goldstein W. B., Poker N. Multiple myeloma involving the gastrointestinal tract. Gastroenterology. 1966 Jul;51(1):87–93. [PubMed] [Google Scholar]
  6. HERSKOVIC T., BARTHOLOMEW L. G., GREEN P. A. AMYLOIDOSIS AND MALABSORPTION SYNDROME. Arch Intern Med. 1964 Nov;114:629–633. doi: 10.1001/archinte.1964.03860110099009. [DOI] [PubMed] [Google Scholar]
  7. Kopeć M., Swierczyńska Z., Pazdur J., Luft S., Plachecka M., Dabska M., Glińska D., Woźniczko-Orlowska G. Diffuse lymphoma of the intestines with a monoclonal gammopathy of IgG3 kappa type. Am J Med. 1974 Mar;56(3):381–385. doi: 10.1016/0002-9343(74)90619-6. [DOI] [PubMed] [Google Scholar]
  8. Levinson J. D., Kirsner J. B. Infiltrative diseases of the small bowel and malabsorption. Am J Dig Dis. 1970 Aug;15(8):741–766. doi: 10.1007/BF02235996. [DOI] [PubMed] [Google Scholar]
  9. Marano R., Dammacco F., Pastore G., Schiraldi O. A case of IgAL-myelomatosis involving the intestinal tract. Digestion. 1970;3(5):294–302. doi: 10.1159/000197047. [DOI] [PubMed] [Google Scholar]
  10. Pruzanski W., Warren R. E., Goldie J. H., Katz A. Malabsorption syndrome with infiltration of the intestinal wall by extracellular monoclonal macroglobulin. Am J Med. 1973 Jun;54(6):811–818. doi: 10.1016/0002-9343(73)90070-3. [DOI] [PubMed] [Google Scholar]
  11. Ruoff M., Lindner A. E., Marshak R. H. Malabsorption syndrome with plasma cell infiltration of the small bowel. Am J Gastroenterol. 1971 Jun;55(6):602–608. [PubMed] [Google Scholar]
  12. Seligmann M., Danon F., Hurez D., Mihaesco E., Preud'homme J. L. Alpha-chain disease: a new immunoglobulin abnormality. Science. 1968 Dec 20;162(3860):1396–1397. doi: 10.1126/science.162.3860.1396. [DOI] [PubMed] [Google Scholar]

Articles from Canadian Medical Association Journal are provided here courtesy of Canadian Medical Association

RESOURCES