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The Journal of the Royal College of General Practitioners logoLink to The Journal of the Royal College of General Practitioners
. 1986 Dec;36(293):547–548.

A search for subclinical infection during a small outbreak of whooping cough: implications for clinical diagnosis

Douglas Jenkinson, Jacqueline D Pepper
PMCID: PMC1960673  PMID: 3668903

Abstract

The transmission of whooping cough in a general practice community was followed after the identification of the first case for nearly three years. Intensive case-finding was undertaken to detect contacts of known cases of whooping cough and to take pernasal swabs from those with any cough; 102 swabs were taken. In three months 39 cases of whooping cough were clinically diagnosed, 17 (44%) of which were confirmed bacteriologically. All had a prolonged paroxysmal cough, one-third reported a catarrhal phase, 18 (46%) vomited with paroxysms and nine (23%) whooped. No isolations of Bordetella pertussis were obtained from the 84 contacts with non-paroxysmal coughs. There was no evidence that subclinical bordetella infection (showing none of the signs of whooping cough) is a common occurrence.

It is probable that many recognizable cases of whooping cough are missed because it can be a milder illness than is often realized and commonly exhibits neither whooping, vomiting nor a catarrhal phase. Paroxysms may be infrequent. The diagnosis of whooping cough should be suspected from a prolonged paroxysmal cough alone.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. GORDON J. E., HOOD R. I. Whooping cough and its epidemiological anomalies. Am J Med Sci. 1951 Sep;222(3):333–361. doi: 10.1097/00000441-195109000-00011. [DOI] [PubMed] [Google Scholar]
  2. Jenkinson D. Outbreak of whooping cough in general practice. Br Med J. 1978 Aug 19;2(6136):577–578. [PMC free article] [PubMed] [Google Scholar]
  3. Jenkinson D., Pepper J. D. Whooping cough. Practitioner. 1982 Sep;226(1371):1479–1487. [PubMed] [Google Scholar]
  4. Johnston I. D., Anderson H. R., Lambert H. P. The severity of whooping cough in hospitalised children--is it declining? J Hyg (Lond) 1985 Apr;94(2):151–161. doi: 10.1017/s0022172400061350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Linnemann C. C., Jr, Bass J. W., Smith M. H. The carrier state in pertussis. Am J Epidemiol. 1968 Nov;88(3):422–427. doi: 10.1093/oxfordjournals.aje.a120903. [DOI] [PubMed] [Google Scholar]
  6. Pollock T. M., Miller E., Lobb J. Severity of whooping cough in England before and after the decline in pertussis immunisation. Arch Dis Child. 1984 Feb;59(2):162–165. doi: 10.1136/adc.59.2.162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Robinson D. A., Mandal B. K., Ironside A. G., Dunbar E. M. Whooping cough--a study of severity in hospital cases. Arch Dis Child. 1981 Sep;56(9):687–691. doi: 10.1136/adc.56.9.687. [DOI] [PMC free article] [PubMed] [Google Scholar]

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