Abstract
The transmission of whooping cough in a general practice community was followed after the identification of the first case for nearly three years. Intensive case-finding was undertaken to detect contacts of known cases of whooping cough and to take pernasal swabs from those with any cough; 102 swabs were taken. In three months 39 cases of whooping cough were clinically diagnosed, 17 (44%) of which were confirmed bacteriologically. All had a prolonged paroxysmal cough, one-third reported a catarrhal phase, 18 (46%) vomited with paroxysms and nine (23%) whooped. No isolations of Bordetella pertussis were obtained from the 84 contacts with non-paroxysmal coughs. There was no evidence that subclinical bordetella infection (showing none of the signs of whooping cough) is a common occurrence.
It is probable that many recognizable cases of whooping cough are missed because it can be a milder illness than is often realized and commonly exhibits neither whooping, vomiting nor a catarrhal phase. Paroxysms may be infrequent. The diagnosis of whooping cough should be suspected from a prolonged paroxysmal cough alone.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- GORDON J. E., HOOD R. I. Whooping cough and its epidemiological anomalies. Am J Med Sci. 1951 Sep;222(3):333–361. doi: 10.1097/00000441-195109000-00011. [DOI] [PubMed] [Google Scholar]
- Jenkinson D. Outbreak of whooping cough in general practice. Br Med J. 1978 Aug 19;2(6136):577–578. [PMC free article] [PubMed] [Google Scholar]
- Jenkinson D., Pepper J. D. Whooping cough. Practitioner. 1982 Sep;226(1371):1479–1487. [PubMed] [Google Scholar]
- Johnston I. D., Anderson H. R., Lambert H. P. The severity of whooping cough in hospitalised children--is it declining? J Hyg (Lond) 1985 Apr;94(2):151–161. doi: 10.1017/s0022172400061350. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Linnemann C. C., Jr, Bass J. W., Smith M. H. The carrier state in pertussis. Am J Epidemiol. 1968 Nov;88(3):422–427. doi: 10.1093/oxfordjournals.aje.a120903. [DOI] [PubMed] [Google Scholar]
- Pollock T. M., Miller E., Lobb J. Severity of whooping cough in England before and after the decline in pertussis immunisation. Arch Dis Child. 1984 Feb;59(2):162–165. doi: 10.1136/adc.59.2.162. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Robinson D. A., Mandal B. K., Ironside A. G., Dunbar E. M. Whooping cough--a study of severity in hospital cases. Arch Dis Child. 1981 Sep;56(9):687–691. doi: 10.1136/adc.56.9.687. [DOI] [PMC free article] [PubMed] [Google Scholar]
