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Journal of Bacteriology logoLink to Journal of Bacteriology
. 1993 Feb;175(3):902–904. doi: 10.1128/jb.175.3.902-904.1993

Positive regulation of the Escherichia coli glycine cleavage enzyme system.

R L Wilson 1, P S Steiert 1, G V Stauffer 1
PMCID: PMC196242  PMID: 8423160

Abstract

A new mutation in Escherichia coli, designated gcvA1, that results in noninducible expression of both gcv and a gcvT-lacZ gene fusion was isolated. A plasmid carrying the wild-type gcvA gene complemented the mutation and restored glycine-inducible gcv and gcvT-lacZ gene expression. These results suggest that gcvA encodes a positive-acting regulatory protein that acts in trans to increase expression of gcv.

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Selected References

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