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. 1993 Aug;68(2):290–294. doi: 10.1038/bjc.1993.330

Detection of an oestrogen receptor-like protein in human meningiomas by band shift assay using a synthetic oestrogen responsive element (ERE).

S G Koehorst 1, H M Jacobs 1, J H Thijssen 1, M A Blankenstein 1
PMCID: PMC1968567  PMID: 8347484

Abstract

When a ligand binding or enzyme immunoassay is used, meningiomas are found to be rich in progestin receptors (PR) whereas oestrogen receptors (ER) are virtually undetectable. A protein that can bind to an oestrogen responsive element (ERE) was detected in meningiomas, by using the band-shift assay. The binding of ER to the ERE is inhibited by the anti-ER monoclonal antibody ER-P31, which is directed to the A/B domain of the ER, indicating that the binding protein is an ER-like protein.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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