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British Journal of Cancer logoLink to British Journal of Cancer
. 1994 Mar;69(3):417–421. doi: 10.1038/bjc.1994.77

eph, the largest known family of putative growth factor receptors.

N L Tuzi 1, W J Gullick 1
PMCID: PMC1968848  PMID: 8123468

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boyd A. W., Ward L. D., Wicks I. P., Simpson R. J., Salvaris E., Wilks A., Welch K., Loudovaris M., Rockman S., Busmanis I. Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line. J Biol Chem. 1992 Feb 15;267(5):3262–3267. [PubMed] [Google Scholar]
  2. Böhme B., Holtrich U., Wolf G., Luzius H., Grzeschik K. H., Strebhardt K., Rübsamen-Waigmann H. PCR mediated detection of a new human receptor-tyrosine-kinase, HEK 2. Oncogene. 1993 Oct;8(10):2857–2862. [PubMed] [Google Scholar]
  3. Cance W. G., Craven R. J., Weiner T. M., Liu E. T. Novel protein kinases expressed in human breast cancer. Int J Cancer. 1993 Jun 19;54(4):571–577. doi: 10.1002/ijc.2910540409. [DOI] [PubMed] [Google Scholar]
  4. Chan J., Watt V. M. eek and erk, new members of the eph subclass of receptor protein-tyrosine kinases. Oncogene. 1991 Jun;6(6):1057–1061. [PubMed] [Google Scholar]
  5. Crews C. M., Alessandrini A., Erikson R. L. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science. 1992 Oct 16;258(5081):478–480. doi: 10.1126/science.1411546. [DOI] [PubMed] [Google Scholar]
  6. Gilardi-Hebenstreit P., Nieto M. A., Frain M., Mattéi M. G., Chestier A., Wilkinson D. G., Charnay P. An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain. Oncogene. 1992 Dec;7(12):2499–2506. [PubMed] [Google Scholar]
  7. Hanks S. K., Quinn A. M., Hunter T. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science. 1988 Jul 1;241(4861):42–52. doi: 10.1126/science.3291115. [DOI] [PubMed] [Google Scholar]
  8. Hirai H., Maru Y., Hagiwara K., Nishida J., Takaku F. A novel putative tyrosine kinase receptor encoded by the eph gene. Science. 1987 Dec 18;238(4834):1717–1720. doi: 10.1126/science.2825356. [DOI] [PubMed] [Google Scholar]
  9. Iwase T., Tanaka M., Suzuki M., Naito Y., Sugimura H., Kino I. Identification of protein-tyrosine kinase genes preferentially expressed in embryo stomach and gastric cancer. Biochem Biophys Res Commun. 1993 Jul 30;194(2):698–705. doi: 10.1006/bbrc.1993.1878. [DOI] [PubMed] [Google Scholar]
  10. Lai C., Lemke G. An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron. 1991 May;6(5):691–704. doi: 10.1016/0896-6273(91)90167-x. [DOI] [PubMed] [Google Scholar]
  11. Lehtola L., Partanen J., Sistonen L., Korhonen J., Wärri A., Härkönen P., Clarke R., Alitalo K. Analysis of tyrosine kinase mRNAs including four FGF receptor mRNAs expressed in MCF-7 breast-cancer cells. Int J Cancer. 1992 Feb 20;50(4):598–603. doi: 10.1002/ijc.2910500419. [DOI] [PubMed] [Google Scholar]
  12. Lemoine N. R., Barnes D. M., Hollywood D. P., Hughes C. M., Smith P., Dublin E., Prigent S. A., Gullick W. J., Hurst H. C. Expression of the ERBB3 gene product in breast cancer. Br J Cancer. 1992 Dec;66(6):1116–1121. doi: 10.1038/bjc.1992.420. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Letwin K., Yee S. P., Pawson T. Novel protein-tyrosine kinase cDNAs related to fps/fes and eph cloned using anti-phosphotyrosine antibody. Oncogene. 1988 Dec;3(6):621–627. [PubMed] [Google Scholar]
  14. Lhoták V., Greer P., Letwin K., Pawson T. Characterization of elk, a brain-specific receptor tyrosine kinase. Mol Cell Biol. 1991 May;11(5):2496–2502. doi: 10.1128/mcb.11.5.2496. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Maru Y., Hirai H., Takaku F. Overexpression confers an oncogenic potential upon the eph gene. Oncogene. 1990 Mar;5(3):445–447. [PubMed] [Google Scholar]
  16. Maru Y., Hirai H., Yoshida M. C., Takaku F. Evolution, expression, and chromosomal location of a novel receptor tyrosine kinase gene, eph. Mol Cell Biol. 1988 Sep;8(9):3770–3776. doi: 10.1128/mcb.8.9.3770. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Nieto M. A., Gilardi-Hebenstreit P., Charnay P., Wilkinson D. G. A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm. Development. 1992 Dec;116(4):1137–1150. doi: 10.1242/dev.116.4.1137. [DOI] [PubMed] [Google Scholar]
  18. Pasquale E. B., Deerinck T. J., Singer S. J., Ellisman M. H. Cek5, a membrane receptor-type tyrosine kinase, is in neurons of the embryonic and postnatal avian brain. J Neurosci. 1992 Oct;12(10):3956–3967. doi: 10.1523/JNEUROSCI.12-10-03956.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Pasquale E. B. Identification of chicken embryo kinase 5, a developmentally regulated receptor-type tyrosine kinase of the Eph family. Cell Regul. 1991 Jul;2(7):523–534. doi: 10.1091/mbc.2.7.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Pawson T., Bernstein A. Receptor tyrosine kinases: genetic evidence for their role in Drosophila and mouse development. Trends Genet. 1990 Nov;6(11):350–356. doi: 10.1016/0168-9525(90)90276-c. [DOI] [PubMed] [Google Scholar]
  21. Petch L. A., Harris J., Raymond V. W., Blasband A., Lee D. C., Earp H. S. A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue. Mol Cell Biol. 1990 Jun;10(6):2973–2982. doi: 10.1128/mcb.10.6.2973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Plowman G. D., Culouscou J. M., Whitney G. S., Green J. M., Carlton G. W., Foy L., Neubauer M. G., Shoyab M. Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1746–1750. doi: 10.1073/pnas.90.5.1746. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Prigent S. A., Lemoine N. R. The type 1 (EGFR-related) family of growth factor receptors and their ligands. Prog Growth Factor Res. 1992;4(1):1–24. doi: 10.1016/0955-2235(92)90002-y. [DOI] [PubMed] [Google Scholar]
  24. Sajjadi F. G., Pasquale E. B. Five novel avian Eph-related tyrosine kinases are differentially expressed. Oncogene. 1993 Jul;8(7):1807–1813. [PubMed] [Google Scholar]
  25. Sajjadi F. G., Pasquale E. B., Subramani S. Identification of a new eph-related receptor tyrosine kinase gene from mouse and chicken that is developmentally regulated and encodes at least two forms of the receptor. New Biol. 1991 Aug;3(8):769–778. [PubMed] [Google Scholar]
  26. Ullrich A., Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell. 1990 Apr 20;61(2):203–212. doi: 10.1016/0092-8674(90)90801-k. [DOI] [PubMed] [Google Scholar]
  27. Vu T. H., Martin G. R., Lee P., Mark D., Wang A., Williams L. T. Developmentally regulated use of alternative promoters creates a novel platelet-derived growth factor receptor transcript in mouse teratocarcinoma and embryonic stem cells. Mol Cell Biol. 1989 Oct;9(10):4563–4567. doi: 10.1128/mcb.9.10.4563. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Wicks I. P., Wilkinson D., Salvaris E., Boyd A. W. Molecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines. Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1611–1615. doi: 10.1073/pnas.89.5.1611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Yarden Y., Ullrich A. Growth factor receptor tyrosine kinases. Annu Rev Biochem. 1988;57:443–478. doi: 10.1146/annurev.bi.57.070188.002303. [DOI] [PubMed] [Google Scholar]

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