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. 1994 Mar;69(3):613–616. doi: 10.1038/bjc.1994.114

Mucin-associated sialosyl-Tn antigen expression in gastric cancer correlates with an adverse outcome.

J L Werther 1, S Rivera-MacMurray 1, H Bruckner 1, M Tatematsu 1, S H Itzkowitz 1
PMCID: PMC1968851  PMID: 8123499

Abstract

The expression of sialosyl-Tn (STn) antigen was evaluated by immunohistochemistry in primary gastric cancers. Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type. Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P < 0.002). STn may be a useful prognostic marker in patients with gastric cancer.

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Selected References

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