Abstract
The relationship between skin tumours in man and exposure to polyaromatic hydrocarbons has been studied in lathe operators exposed to cutting oils. Seven cases of scrotal cancer and 13 cases of senile keratosis and keratoacanthoma were observed. The risk varied as the 1.6th power of duration of exposure for cancer on the scrotum and the 2.4th power for tumours on the hand and forearms. These results accord well with experiments on animals. There was some evidence of an increasing trend in risk with increasing age at first exposure.
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Selected References
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- CRUICKSHANK C. N. D., GOUREVITCH A. Skin cancer of the hand and forearm. Br J Ind Med. 1952 Jan;9(1):74–79. doi: 10.1136/oem.9.1.74. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CRUICKSHANK C. N. D., SQUIRE J. R. Skin cancer in the engineering industry from the use of mineral oil. Br J Ind Med. 1950 Jan;7(1):1–11. doi: 10.1136/oem.7.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Järvholm B., Fast K., Lavenius B., Tomsic P. Exposure to cutting oils and its relation to skin tumors and premalignant skin lesions on the hands and forearms. Scand J Work Environ Health. 1985 Oct;11(5):365–369. doi: 10.5271/sjweh.2211. [DOI] [PubMed] [Google Scholar]
- Järvholm B., Lavenius B. Mortality and cancer morbidity in workers exposed to cutting fluids. Arch Environ Health. 1987 Nov-Dec;42(6):361–366. doi: 10.1080/00039896.1987.9934360. [DOI] [PubMed] [Google Scholar]
- Lee P. N., O'Neill J. A. The effect both of time and dose applied on tumour incidence rate in benzopyrene skin painting experiments. Br J Cancer. 1971 Dec;25(4):759–770. doi: 10.1038/bjc.1971.90. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MASTROMATTEO E. Cutting oils and squamous-cell carcinoma. I. Incidence in a plant with a report of six cases. Br J Ind Med. 1955 Jul;12(3):240–243. doi: 10.1136/oem.12.3.240. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peto R., Roe F. J., Lee P. N., Levy L., Clack J. Cancer and ageing in mice and men. Br J Cancer. 1975 Oct;32(4):411–426. doi: 10.1038/bjc.1975.242. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thony C., Thony J., Lafontaine M., Limasset J. C. Hydrocarbures polycycliques aromatiques cancerogenes dans les produits pétroliers: préventions possibles du cancer des huiles minérales. IARC Sci Publ. 1976;(13):165–170. [PubMed] [Google Scholar]
- Waldron H. A. A brief history of scrotal cancer. Br J Ind Med. 1983 Nov;40(4):390–401. doi: 10.1136/oem.40.4.390. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Waldron H. A., Waterhouse J. A., Tessema N. Scrotal cancer in the West Midlands 1936-76. Br J Ind Med. 1984 Nov;41(4):437–444. doi: 10.1136/oem.41.4.437. [DOI] [PMC free article] [PubMed] [Google Scholar]