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British Journal of Cancer logoLink to British Journal of Cancer
. 1991 Apr;63(4):634–635. doi: 10.1038/bjc.1991.145

A comparison of the clinical metastatic patterns of invasive lobular and ductal carcinomas of the breast.

A R Dixon 1, I O Ellis 1, C W Elston 1, R W Blamey 1
PMCID: PMC1972371  PMID: 1850613

Abstract

Seventy seven patients with metastases from an invasive lobular carcinoma of the breast have been compared with 72 consecutive metastatic ductal carcinomas. There was no difference in the metastatic free interval between the two groups. A distinct pattern of clinical presentation of metastases was seen; hepatic (P = 0.01) and peritoneal metastases (P = 0.0003) occurred more commonly in lobular tumours. Bilateral cancers were more common in the lobular group (P = 0.01). No difference was seen in terms of meningeal and pulmonary metastases. Survival after metastases was significantly longer in patients with metastatic lobular carcinoma (P = 0.02).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amer M. H. Chemotherapy and pattern of metastases in breast cancer patients. J Surg Oncol. 1982 Feb;19(2):101–105. doi: 10.1002/jso.2930190212. [DOI] [PubMed] [Google Scholar]
  2. Ashikari R., Huvos A. G., Urban J. A., Robbins G. F. Infiltrating lobular carcinoma of the breast. Cancer. 1973 Jan;31(1):110–116. doi: 10.1002/1097-0142(197301)31:1<110::aid-cncr2820310115>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
  3. Cifuentes N., Pickren J. W. Metastases from carcinoma of mammary gland: an autopsy study. J Surg Oncol. 1979;11(3):193–205. doi: 10.1002/jso.2930110303. [DOI] [PubMed] [Google Scholar]
  4. Dixon J. M., Anderson T. J., Page D. L., Lee D., Duffy S. W. Infiltrating lobular carcinoma of the breast. Histopathology. 1982 Mar;6(2):149–161. doi: 10.1111/j.1365-2559.1982.tb02712.x. [DOI] [PubMed] [Google Scholar]
  5. Dixon J. M., Page D. L., Anderson T. J., Lee D., Elton R. A., Stewart H. J., Forrest A. P. Long-term survivors after breast cancer. Br J Surg. 1985 Jun;72(6):445–448. doi: 10.1002/bjs.1800720614. [DOI] [PubMed] [Google Scholar]
  6. Fisher E. R., Gregorio R. M., Fisher B., Redmond C., Vellios F., Sommers S. C. The pathology of invasive breast cancer. A syllabus derived from findings of the National Surgical Adjuvant Breast Project (protocol no. 4). Cancer. 1975 Jul;36(1):1–85. doi: 10.1002/1097-0142(197507)36:1<1::aid-cncr2820360102>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
  7. Haagensen C. D., Lane N., Lattes R., Bodian C. Lobular neoplasia (so-called lobular carcinoma in situ) of the breast. Cancer. 1978 Aug;42(2):737–769. doi: 10.1002/1097-0142(197808)42:2<737::aid-cncr2820420247>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
  8. Harris M., Howell A., Chrissohou M., Swindell R. I., Hudson M., Sellwood R. A. A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast. Br J Cancer. 1984 Jul;50(1):23–30. doi: 10.1038/bjc.1984.135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep. 1966 Mar;50(3):163–170. [PubMed] [Google Scholar]
  10. Martinez V., Azzopardi J. G. Invasive lobular carcinoma of the breast: incidence and variants. Histopathology. 1979 Nov;3(6):467–488. doi: 10.1111/j.1365-2559.1979.tb03029.x. [DOI] [PubMed] [Google Scholar]
  11. Nielsen M., Christensen L., Andersen J. Contralateral cancerous breast lesions in women with clinical invasive breast carcinoma. Cancer. 1986 Mar 1;57(5):897–903. doi: 10.1002/1097-0142(19860301)57:5<897::aid-cncr2820570502>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
  12. Rosen P. P., Kosloff C., Lieberman P. H., Adair F., Braun D. W., Jr Lobular carcinoma in situ of the breast. Detailed analysis of 99 patients with average follow-up of 24 years. Am J Surg Pathol. 1978 Sep;2(3):225–251. doi: 10.1097/00000478-197809000-00001. [DOI] [PubMed] [Google Scholar]
  13. Urban J. A. Bilaterality of cancer of the breast. Biopsy of the opposite breast. Cancer. 1967 Nov;20(11):1867–1870. doi: 10.1002/1097-0142(196711)20:11<1867::aid-cncr2820201111>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  14. Viadana E., Cotter R., Pickren J. W., Bross I. D. An autopsy study of metastatic sites of breast cancer. Cancer Res. 1973 Jan;33(1):179–181. [PubMed] [Google Scholar]
  15. Wheeler J. E., Enterline H. T. Lobular carcinoma of the breast in situ and infiltrating. Pathol Annu. 1976;11:161–188. [PubMed] [Google Scholar]

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