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. 1991 Jun;63(6):1021–1023. doi: 10.1038/bjc.1991.222

Expression of cytochrome P450IA in breast cancer.

G I Murray 1, C O Foster 1, T S Barnes 1, R J Weaver 1, S W Ewen 1, W T Melvin 1, M D Burke 1
PMCID: PMC1972525  PMID: 2069838

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BLOOM H. J., RICHARDSON W. W. Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer. 1957 Sep;11(3):359–377. doi: 10.1038/bjc.1957.43. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Barnes T. S., Shaw P. M., Burke M. D., Melvin W. T. Monoclonal antibodies against human cytochrome P-450 recognizing different pregnenolone 16 alpha-carbonitrile-inducible rat cytochromes P-450. Biochem J. 1987 Nov 15;248(1):301–304. doi: 10.1042/bj2480301. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Buchmann A., Kuhlmann W., Schwarz M., Kunz W., Wolf C. R., Moll E., Friedberg T., Oesch F. Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in preneoplastic and neoplastic lesions in rat liver. Carcinogenesis. 1985 Apr;6(4):513–521. doi: 10.1093/carcin/6.4.513. [DOI] [PubMed] [Google Scholar]
  4. Elston C. W. The assessment of histological differentiation in breast cancer. Aust N Z J Surg. 1984 Feb;54(1):11–15. doi: 10.1111/j.1445-2197.1984.tb06677.x. [DOI] [PubMed] [Google Scholar]
  5. Fitzpatrick F. A., Murphy R. C. Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of "epoxygenase"-derived eicosanoids. Pharmacol Rev. 1988 Dec;40(4):229–241. [PubMed] [Google Scholar]
  6. Gierthy J. F., Lincoln D. W., 2nd, Kampcik S. J., Dickerman H. W., Bradlow H. L., Niwa T., Swaneck G. E. Enhancement of 2- and 16 alpha-estradiol hydroxylation in MCF-7 human breast cancer cells by 2,3,7,8-tetrachlorodibenzo-P-dioxin. Biochem Biophys Res Commun. 1988 Dec 15;157(2):515–520. doi: 10.1016/s0006-291x(88)80279-1. [DOI] [PubMed] [Google Scholar]
  7. Gonzalez F. J. Molecular genetics of the P-450 superfamily. Pharmacol Ther. 1990;45(1):1–38. doi: 10.1016/0163-7258(90)90006-n. [DOI] [PubMed] [Google Scholar]
  8. Graham M. J., Lucier G. W., Linko P., Maronpot R. R., Goldstein J. A. Increases in cytochrome P-450 mediated 17 beta-estradiol 2-hydroxylase activity in rat liver microsomes after both acute administration and subchronic administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in a two-stage hepatocarcinogenesis model. Carcinogenesis. 1988 Nov;9(11):1935–1941. doi: 10.1093/carcin/9.11.1935. [DOI] [PubMed] [Google Scholar]
  9. Guengerich F. P. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res. 1988 Jun 1;48(11):2946–2954. [PubMed] [Google Scholar]
  10. Ioannides C., Parke D. V. The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals. Drug Metab Rev. 1990;22(1):1–85. doi: 10.3109/03602539008991444. [DOI] [PubMed] [Google Scholar]
  11. Lipton A., Santner S. J., Santen R. J., Harvey H. A., Feil P. D., White-Hershey D., Bartholomew M. J., Antle C. E. Aromatase activity in primary and metastatic human breast cancer. Cancer. 1987 Feb 15;59(4):779–782. doi: 10.1002/1097-0142(19870215)59:4<779::aid-cncr2820590419>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]
  12. McLemore T. L., Adelberg S., Liu M. C., McMahon N. A., Yu S. J., Hubbard W. C., Czerwinski M., Wood T. G., Storeng R., Lubet R. A. Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas. J Natl Cancer Inst. 1990 Aug 15;82(16):1333–1339. doi: 10.1093/jnci/82.16.1333. [DOI] [PubMed] [Google Scholar]
  13. Murray G. I., Barnes T. S., Sewell H. F., Ewen S. W., Melvin W. T., Shaw P. M., Fowler J., Burke M. D. Cytochrome P-450 localization in normal human adult and foetal liver by immunocytochemistry using a monoclonal antibody against human cytochrome P-450. Histochem J. 1987 Oct-Nov;19(10-11):537–545. doi: 10.1007/BF01687361. [DOI] [PubMed] [Google Scholar]
  14. Nebert D. W., Gonzalez F. J. P450 genes: structure, evolution, and regulation. Annu Rev Biochem. 1987;56:945–993. doi: 10.1146/annurev.bi.56.070187.004501. [DOI] [PubMed] [Google Scholar]
  15. Newton C. J., Samuel D. L., James V. H. Aromatase activity and concentrations of cortisol, progesterone and testosterone in breast and abdominal adipose tissue. J Steroid Biochem. 1986 May;24(5):1033–1039. doi: 10.1016/0022-4731(86)90356-0. [DOI] [PubMed] [Google Scholar]
  16. Roomi M. W., Ho R. K., Sarma D. S., Farber E. A common biochemical pattern in preneoplastic hepatocyte nodules generated in four different models in the rat. Cancer Res. 1985 Feb;45(2):564–571. [PubMed] [Google Scholar]
  17. Schneider J., Huh M. M., Bradlow H. L., Fishman J. Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells. J Biol Chem. 1984 Apr 25;259(8):4840–4845. [PubMed] [Google Scholar]
  18. Stout D. L., Becker F. F. Xenobiotic metabolizing enzymes in genetically and chemically initiated mouse liver tumors. Cancer Res. 1986 Jun;46(6):2693–2696. [PubMed] [Google Scholar]
  19. el Mouelhi M., Didolkar M. S., Elias E. G., Guengerich F. P., Kauffman F. C. Hepatic drug-metabolizing enzymes in primary and secondary tumors of human liver. Cancer Res. 1987 Jan 15;47(2):460–466. [PubMed] [Google Scholar]

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