Abstract
Computed tomographic scanning of the chest in 100 patients with newly diagnosed malignant lymphoma detected mediastinal lymphadenopathy (39%) and parenchymal deposits (15%) with a significantly greater sensitivity and specificity than conventional radiological techniques. This principally affected the staging and treatment of patients with limited stage disease. The stage was changed in 10/61 patients (16%) with Stages I-III prior to CT scan and treatment was altered in 11/29 (38%) patients for whom radiation was the treatment of choice. Complete remissions as defined by CT scan have been more durable than those defined by CXR alone.
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- Baron R. L., Levitt R. G., Sagel S. S., Stanley R. J. Computed tomography in the evaluation of mediastinal widening. Radiology. 1981 Jan;138(1):107–113. doi: 10.1148/radiology.138.1.7455069. [DOI] [PubMed] [Google Scholar]
- Carbone P. P., Kaplan H. S., Musshoff K., Smithers D. W., Tubiana M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res. 1971 Nov;31(11):1860–1861. [PubMed] [Google Scholar]
- Chabner B. A., Johnson R. E., DeVita V. T., Canellos G. P., Hubbard S. P., Johnson S. K., Young R. C. Sequential staging in non-Hodgkin's lymphoma. Cancer Treat Rep. 1977 Sep;61(6):993–997. [PubMed] [Google Scholar]
- Ellert J., Kreel L. The role of computed tomography in the initial staging and subsequent management of the lymphomas. J Comput Assist Tomogr. 1980 Jun;4(3):368–391. doi: 10.1097/00004728-198006000-00014. [DOI] [PubMed] [Google Scholar]
- Fon G. T., Bein M. E., Mancuso A. A., Keesey J. C., Lupetin A. R., Wong W. S. Computed tomography of the anterior mediastinum in myasthenia gravis. A radiologic-pathologic correlative study. Radiology. 1982 Jan;142(1):135–141. doi: 10.1148/radiology.142.1.7053523. [DOI] [PubMed] [Google Scholar]
- Lee C. K., Bloomfield C. D., Goldman A. I., Levitt S. H. Prognostic significance of mediastinal involvement in Hodgkin's disease treated with curative radiotherapy. Cancer. 1980 Dec 1;46(11):2403–2409. doi: 10.1002/1097-0142(19801201)46:11<2403::aid-cncr2820461116>3.0.co;2-9. [DOI] [PubMed] [Google Scholar]
- Lister T. A., Cullen M. H., Beard M. E., Brearley R. L., Whitehouse J. M., Wrigley P. F., Stansfeld A. G., Sutcliffe S. B., Malpas J. S., Crowther D. Comparison of combined and single-agent chemotherapy in non-Hodgkin's lymphoma of favourable histological type. Br Med J. 1978 Mar 4;1(6112):533–537. doi: 10.1136/bmj.1.6112.533. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mauch P., Goodman R., Hellman S. The significance of mediastinal involvement in early stage Hodgkin's disease. Cancer. 1978 Sep;42(3):1039–1045. doi: 10.1002/1097-0142(197809)42:3<1039::aid-cncr2820420302>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
- Muhm J. R., Brown L. R., Crowe J. K., Sheedy P. F., 2nd, Hattery R. R., Stephens D. H. Comparison of whole lung tomography and computed tomography for detecting pulmonary nodules. AJR Am J Roentgenol. 1978 Dec;131(6):981–984. doi: 10.2214/ajr.131.6.981. [DOI] [PubMed] [Google Scholar]
- Osborne D. R., Korobkin M., Ravin C. E., Putman C. E., Wolfe W. G., Sealy W. C., Young W. G., Breiman R., Heaston D., Ram P. Comparison of plain radiography, conventional tomography, and computed tomography in detecting intrathoracic lymph node metastases from lung carcinoma. Radiology. 1982 Jan;142(1):157–161. doi: 10.1148/radiology.142.1.7053525. [DOI] [PubMed] [Google Scholar]
- Potchen E. J. Editorial: Diagnostic radiology--planning for the future. Radiology. 1976 Jul;120(1):227–229. doi: 10.1148/120.1.227. [DOI] [PubMed] [Google Scholar]
- ROSENBERG S. A., DIAMOND H. D., JASLOWITZ B., CRAVER L. F. Lymphosarcoma: a review of 1269 cases. Medicine (Baltimore) 1961 Feb;40:31–84. doi: 10.1097/00005792-196102000-00002. [DOI] [PubMed] [Google Scholar]
- Sutcliffe S. B., Wrigley P. F., Peto J., Lister T. A., Stansfeld A. G., Whitehouse J. M., Crowther D., Malpas J. S. MVPP chemotherapy regimen for advanced Hodgkin's disease. Br Med J. 1978 Mar 18;1(6114):679–683. doi: 10.1136/bmj.1.6114.679. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sutcliffe S. B., Wrigley P. F., Timothy A. R., Dorreen M. A., Shand W. S., Stansfeld A. G., Jones A. E., Malpas J. S., Lister T. A. Posttreatment laparotomy as a guide to management in patients with Hodgkin's disease. Cancer Treat Rep. 1982 Apr;66(4):759–765. [PubMed] [Google Scholar]
- Underwood G. H., Jr, Hooper R. G., Axelbaum S. P., Goodwin D. W. Computed tomographic scanning of the thorax in the staging of bronchogenic carcinoma. N Engl J Med. 1979 Apr 5;300(14):777–778. doi: 10.1056/NEJM197904053001407. [DOI] [PubMed] [Google Scholar]




