Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Babson J. R., Reed D. J. Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates. Biochem Biophys Res Commun. 1978 Jul 28;83(2):754–762. doi: 10.1016/0006-291x(78)91053-7. [DOI] [PubMed] [Google Scholar]
- Hilton J., Walker M. D. Hydroxylation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Biochem Pharmacol. 1975 Dec 1;24(23):2153–2158. doi: 10.1016/0006-2952(75)90045-3. [DOI] [PubMed] [Google Scholar]
- Kann H. E., Jr, Schott M. A., Petkas A. Effects of structure and chemical activity on the ability of nitrosoureas to inhibit DNA repair. Cancer Res. 1980 Jan;40(1):50–55. [PubMed] [Google Scholar]
- Lee F. Y., Workman P. Modification of CCNU pharmacokinetics by misonidazole--a major mechanism of chemosensitization in mice. Br J Cancer. 1983 May;47(5):659–669. doi: 10.1038/bjc.1983.104. [DOI] [PMC free article] [PubMed] [Google Scholar]
- May H. E., Boose R., Reed D. J. Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes. Biochem Biophys Res Commun. 1974 Mar 25;57(2):426–433. doi: 10.1016/0006-291x(74)90948-6. [DOI] [PubMed] [Google Scholar]
- Montgomery J. A., James R., McCaleb G. S., Johnston T. P. The modes of decomposition of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds. J Med Chem. 1967 Jul;10(4):668–674. doi: 10.1021/jm00316a033. [DOI] [PubMed] [Google Scholar]
- Mulcahy R. T. Chemical properties of nitrosoureas: implications for interaction with misonidazole. Int J Radiat Oncol Biol Phys. 1982 Mar-Apr;8(3-4):599–602. doi: 10.1016/0360-3016(82)90692-7. [DOI] [PubMed] [Google Scholar]
- Mulcahy R. T., Dembs N. L., Ublacker G. A. Enhancement of nitrosourea cytotoxicity by misonidazole in vitro: correlation with carbamoylating potential. Br J Cancer. 1984 Mar;49(3):307–313. doi: 10.1038/bjc.1984.48. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Siemann D. W. Potentiation of chemotherapy by hypoxic cell radiation sensitizers--a review. Int J Radiat Oncol Biol Phys. 1982 Jun;8(6):1029–1034. doi: 10.1016/0360-3016(82)90172-9. [DOI] [PubMed] [Google Scholar]
- Wheeler G. P., Bowdon B. J., Grimsley J. A., Lloyd H. H. Interrelationships of some chemical, physicochemical, and biological activities of several 1-(2-haloethyl)-1-nitrosoureas. Cancer Res. 1974 Jan;34(1):194–200. [PubMed] [Google Scholar]
- Wheeler G. P., Johnston T. P., Bowdon B. J., McCaleb G. S., Hill D. L., Montgomery J. A. Comparison of the properties of metabolites of CCNU. Biochem Pharmacol. 1977 Dec 15;26(24):2331–2336. doi: 10.1016/0006-2952(77)90436-1. [DOI] [PubMed] [Google Scholar]
