Skip to main content
NCBI home page
British Journal of Cancer logoLink to British Journal of Cancer
. 1985 Nov;52(5):789–792. doi: 10.1038/bjc.1985.259

Antitumour imidazotetrazines--XI: Effect of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one [CCRG 81045; M and B 39831 NSC 362856] on poly(ADP-ribose) metabolism.

M J Tisdale
PMCID: PMC1977218  PMID: 3864485

Full text

PDF
789

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berger N. A., Weber G., Kaichi A. S., Petzold S. J. Relation of poly(adenosine diphosphoribose) synthesis to DNA synthesis and cell growth. Biochim Biophys Acta. 1978 Jun 22;519(1):105–117. doi: 10.1016/0005-2787(78)90065-5. [DOI] [PubMed] [Google Scholar]
  2. Erickson L. C., Bradley M. O., Kohn K. W. Measurements of DNA damage in Chinese hamster cells treated with equitoxic and equimutagenic doses of nitrosoureas. Cancer Res. 1978 Oct;38(10):3379–3384. [PubMed] [Google Scholar]
  3. Farzaneh F., Zalin R., Brill D., Shall S. DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation. Nature. 1982 Nov 25;300(5890):362–366. doi: 10.1038/300362a0. [DOI] [PubMed] [Google Scholar]
  4. Gibson N. W., Erickson L. C., Hickman J. A. Effects of the antitumor agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one on the DNA of mouse L1210 cells. Cancer Res. 1984 May;44(5):1767–1771. [PubMed] [Google Scholar]
  5. Gibson N. W., Hickman J. A., Erickson L. C. DNA cross-linking and cytotoxicity in normal and transformed human cells treated in vitro with 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d] -1,2,3,5-tetrazin-4(3H)-one. Cancer Res. 1984 May;44(5):1772–1775. [PubMed] [Google Scholar]
  6. Halldorsson H., Gray D. A., Shall S. Poly (ADP-ribose) polymerase activity in nucleotide permeable cells. FEBS Lett. 1978 Jan 15;85(2):349–352. doi: 10.1016/0014-5793(78)80489-x. [DOI] [PubMed] [Google Scholar]
  7. Horgan C. M., Tisdale M. J. Antitumour imidazotetrazines--IV. An investigation into the mechanism of antitumour activity of a novel and potent antitumour agent, mitozolomide (CCRG 81010, M & B 39565; NSC 353451). Biochem Pharmacol. 1984 Jul 15;33(14):2185–2192. doi: 10.1016/0006-2952(84)90652-x. [DOI] [PubMed] [Google Scholar]
  8. Horgan C. M., Tisdale M. J. Antitumour imidazotetrazines--VIII. Uptake and decomposition of a novel antitumour agent mitozolomide (CCRG 81010; M and B 39565; NSC 353451) in TLX5 mouse lymphoma in vitro. Biochem Pharmacol. 1985 Jan 15;34(2):217–221. doi: 10.1016/0006-2952(85)90127-3. [DOI] [PubMed] [Google Scholar]
  9. Johnstone A. P., Williams G. T. Role of DNA breaks and ADP-ribosyl transferase activity in eukaryotic differentiation demonstrated in human lymphocytes. Nature. 1982 Nov 25;300(5890):368–370. doi: 10.1038/300368a0. [DOI] [PubMed] [Google Scholar]
  10. Kanai M., Miwa M., Kondo T., Tanaka Y., Nakayasu M., Sugimura T. Involvement of poly (ADP-ribose) metabolism in induction of differentiation of HL-60 promyelocytic leukemia cells. Biochem Biophys Res Commun. 1982 Mar 30;105(2):404–411. doi: 10.1016/0006-291x(82)91448-6. [DOI] [PubMed] [Google Scholar]
  11. Pulito V. L., Miller D. L., Sassa S., Yamane T. ADP-ribosyltransferase activity during the friend virus-induced murine erythroleukemia cell differentiation. J Biol Chem. 1983 Dec 25;258(24):14756–14758. [PubMed] [Google Scholar]
  12. Rowley P. T., Ohlsson-Wilhelm B. M., Farley B. A., LaBella S. Inducers of erythroid differentiation in K562 human leukemia cells. Exp Hematol. 1981 Jan;9(1):32–37. [PubMed] [Google Scholar]
  13. Skidmore C. J., Davies M. I., Goodwin P. M., Halldorsson H., Lewis P. J., Shall S., Zia'ee A. A. The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by gamma-radiation and N-methyl-N-nitrosourea. Eur J Biochem. 1979 Nov 1;101(1):135–142. doi: 10.1111/j.1432-1033.1979.tb04225.x. [DOI] [PubMed] [Google Scholar]
  14. Stevens M. F., Hickman J. A., Stone R., Gibson N. W., Baig G. U., Lunt E., Newton C. G. Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent. J Med Chem. 1984 Feb;27(2):196–201. doi: 10.1021/jm00368a016. [DOI] [PubMed] [Google Scholar]
  15. Tisdale M. J. Induction of haemoglobin synthesis in the human leukaemia cell line K562 by monomethyltriazenes and imidazotetrazinones. Biochem Pharmacol. 1985 Jun 15;34(12):2077–2082. doi: 10.1016/0006-2952(85)90398-3. [DOI] [PubMed] [Google Scholar]
  16. Whish W. J., Davies M. I., Shall S. Stimulation of poly(ADP-ribose) polymerase activity by the anti-tumour antibiotic, streptozotocin. Biochem Biophys Res Commun. 1975 Jul 22;65(2):722–730. doi: 10.1016/s0006-291x(75)80205-1. [DOI] [PubMed] [Google Scholar]
  17. Williams G. T., Johnstone A. P. ADP-ribosyl transferase, rearrangement of DNA, and cell differentiation. Biosci Rep. 1983 Sep;3(9):815–830. doi: 10.1007/BF01133780. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES