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. 1992 Mar;65(3):355–358. doi: 10.1038/bjc.1992.72

Genetic evidence that placental site trophoblastic tumours can originate from a hydatidiform mole or a normal conceptus.

R A Fisher 1, F J Paradinas 1, E S Newlands 1, G M Boxer 1
PMCID: PMC1977585  PMID: 1348423

Abstract

The genetic origin of two placental site trophoblastic tumours was established using a Y chromosome-specific and locus-specific minisatellite probes. A gestational origin was confirmed for both tumours. In one case the origin of the tumour was consistent with derivation from a normal female conceptus while the other was shown to arise from a homozygous complete hydatidiform mole, an abnormal conceptus more usually associated with the development of choriocarcinoma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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