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. 1991 Sep;64(3):531–533. doi: 10.1038/bjc.1991.344

c-src structure in human cancers with elevated pp60c-src activity.

P Wang 1, F Fromowitz 1, M Koslow 1, N Hagag 1, B Johnson 1, M Viola 1
PMCID: PMC1977675  PMID: 1716952

Abstract

We used RNAase protection and restriction fragment length polymorphism assays to detect activating mutations of c-src in a spectrum of human tumours. No mutations were detected at codons 98, 381, 444, and 530. We conclude that mutational activation is not the mechanism of enhancement of pp60c-src-specific kinase activity found in a number of human cancer types.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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