Skip to main content
NCBI home page
British Journal of Cancer logoLink to British Journal of Cancer
. 1991 Dec;64(6):1182–1186. doi: 10.1038/bjc.1991.487

Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.

G Lundegårdh 1, A Lindgren 1, A Rohul 1, O Nyrén 1, L E Hansson 1, R Bergström 1, H O Adami 1
PMCID: PMC1977875  PMID: 1764385

Abstract

In order to test the hypothesis that the general decline in gastric cancer observed in many countries is due to a selective decline in Laurén's intestinal type, we re-examined all 427 histologic sections obtained from gastric carcinomas diagnosed at the Department of Pathology, University Hospital, Uppsala, Sweden, in 1951, 1961, 1971-72 and 1981. The relative proportions of intestinal and diffuse type cancers were compared. The intestinal type was significantly (P less than 0.001) more common among elderly people than in the younger age groups. The relative proportions of intestinal type carcinoma in the four periods under study were 65%, 55%, 42% and 60%, respectively. The absence of any clearly discernible trend over time contradicts the hypothesis of diverse secular trends for intestinal and diffuse types of gastric carcinoma.

Full text

PDF
1182

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Antonioli D. A., Goldman H. Changes in the location and type of gastric adenocarcinoma. Cancer. 1982 Aug 15;50(4):775–781. doi: 10.1002/1097-0142(19820815)50:4<775::aid-cncr2820500425>3.0.co;2-w. [DOI] [PubMed] [Google Scholar]
  2. Correa P. Clinical implications of recent developments in gastric cancer pathology and epidemiology. Semin Oncol. 1985 Mar;12(1):2–10. [PubMed] [Google Scholar]
  3. Correa P., Cuello C., Duque E. Carcinoma and intestinal metaplasia of the stomach in Colombian migrants. J Natl Cancer Inst. 1970 Feb;44(2):297–306. [PubMed] [Google Scholar]
  4. Correa P., Sasano N., Stemmermann G. N., Haenszel W. Pathology of gastric carcinoma in Japanese populations: comparisons between Miyagi prefecture, Japan, and Hawaii. J Natl Cancer Inst. 1973 Nov;51(5):1449–1459. doi: 10.1093/jnci/51.5.1449. [DOI] [PubMed] [Google Scholar]
  5. Kato Y., Kitagawa T., Nakamura K., Sugano H. Changes in the histologic types of gastric carcinoma in Japan. Cancer. 1981 Nov 1;48(9):2084–2087. doi: 10.1002/1097-0142(19811101)48:9<2084::aid-cncr2820480928>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
  6. Kubo T. Geographical pathology of gastric carcinoma. Acta Pathol Jpn. 1974 Jul;24(4):465–479. doi: 10.1111/j.1440-1827.1974.tb00837.x. [DOI] [PubMed] [Google Scholar]
  7. Kubo T. Histologic appearance of gastric carcinoma in high and low mortality countries: comparison between Kyushu, Japan and Minnesota, USA. Cancer. 1971 Sep;28(3):726–734. doi: 10.1002/1097-0142(197109)28:3<726::aid-cncr2820280331>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]
  8. Kubo T., Tsunoda H., Tanaka S., Soga J. Geographical pathology of gastric carcinoma: a comparative study on histological types between high and low mortality areas in Japan. Gan. 1981 Apr;72(2):235–244. [PubMed] [Google Scholar]
  9. LAUREN P. THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION. Acta Pathol Microbiol Scand. 1965;64:31–49. doi: 10.1111/apm.1965.64.1.31. [DOI] [PubMed] [Google Scholar]
  10. Maartmann-Moe H., Hartveit F. On the reputed decline in gastric carcinoma: necropsy study from western Norway. Br Med J (Clin Res Ed) 1985 Jan 12;290(6462):103–105. doi: 10.1136/bmj.290.6462.103. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Ming S. C. Gastric carcinoma. A pathobiological classification. Cancer. 1977 Jun;39(6):2475–2485. doi: 10.1002/1097-0142(197706)39:6<2475::aid-cncr2820390626>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  12. Muñoz N., Asvall J. Time trends of intestinal and diffuse types of gastric cancer in Norway. Int J Cancer. 1971 Jul 15;8(1):144–157. doi: 10.1002/ijc.2910080118. [DOI] [PubMed] [Google Scholar]
  13. Muñoz N., Connelly R. Time trends of intestinal and diffuse types of gastric cancer in the United States. Int J Cancer. 1971 Jul 15;8(1):158–164. doi: 10.1002/ijc.2910080119. [DOI] [PubMed] [Google Scholar]
  14. Muñoz N., Correa P., Cuello C., Duque E. Histologic types of gastric carcinoma in high- and low-risk areas. Int J Cancer. 1968 Nov 15;3(6):809–818. doi: 10.1002/ijc.2910030614. [DOI] [PubMed] [Google Scholar]
  15. Muñoz N., Matko I. Histological types of gastric cancer and its relationship with intestinal metaplasia. Recent Results Cancer Res. 1972;39:99–105. [PubMed] [Google Scholar]
  16. Sipponen P., Järvi O., Kekki M., Siurala M. Decreased incidences of intestinal and diffuse types of gastric carcinoma in Finland during a 20-year period. Scand J Gastroenterol. 1987 Sep;22(7):865–871. doi: 10.3109/00365528708991927. [DOI] [PubMed] [Google Scholar]
  17. Stemmermann G. N., Brown C. A survival study of intestinal and diffuse types of gastric carcinoma. Cancer. 1974 Apr;33(4):1190–1195. doi: 10.1002/1097-0142(197404)33:4<1190::aid-cncr2820330444>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  18. Teh M., Lee Y. S. Intestinal and diffuse carcinoma of the stomach among the ethnic and dialect groups in Singapore. Cancer. 1987 Aug 15;60(4):921–925. doi: 10.1002/1097-0142(19870815)60:4<921::aid-cncr2820600435>3.0.co;2-z. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES