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. 1992 Sep;66(3):439–443. doi: 10.1038/bjc.1992.293

12-O-tetradecanoylphorbol 13-acetate induced differentiation in human lung squamous carcinoma cells.

G J Rabiasz 1, S P Langdon 1, L Anderson 1, A A Ritchie 1, W R Miller 1, J F Smyth 1
PMCID: PMC1977941  PMID: 1381602

Abstract

Three human lung squamous carcinoma cell lines (NX002, CX140 and CX143) demonstrate features of squamous differentiation including involucrin synthesis and competence to form cornified envelopes. 12-O-Tetradecanoylphorbol 13-acetate inhibits growth of these cell lines and this growth inhibition is associated with enhanced differentiation.

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Selected References

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