Skip to main content
NCBI home page
British Medical Journal logoLink to British Medical Journal
. 1969 Jan 11;1(5636):73–79. doi: 10.1136/bmj.1.5636.73

Bronchopneumonia with Serious Sequelae in Children with Evidence of Adenovirus Type 21 Infection

W R Lang, C W Howden, Jocelyn Laws, J F Burton
PMCID: PMC1981971  PMID: 4302627

Abstract

Twenty-five cases of severe pneumonitis occurring among children aged 3 to 18 months were observed in Auckland, New Zealand, in 1965. An apparent relationship was established between a uniform disease picture and recovery of adenovirus type 21. Two died, and of the survivors 60% had permanent lung damage, probably resulting from obliterative bronchiolitis. Twenty per cent. were left with proved bronchiectasis. The possible relationships of adenovirus pneumonia to malnutrition or a genetic factor on the one hand and to the development of bronchiectasis on the other are discussed.

Full text

PDF
73

Images in this article

76Fig. 1
on p.76
76Fig. 2
on p.76
76Fig. 3
on p.76
76Fig. 4
on p.76
77Fig. 5
on p.77

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BRADSTREET C. M., TAYLOR C. E. Technique of complementfixation test applicable to the diagnosis of virus diseases. Mon Bull Minist Health Public Health Lab Serv. 1962 May;21:96–104. [PubMed] [Google Scholar]
  2. CHANY C., LEPINE P., LELONG M., LE T. V., SATGE P., VIRAT J. Severe and fatal pneumonia in infants and young children associated with adenovirus infections. Am J Hyg. 1958 May;67(3):367–378. doi: 10.1093/oxfordjournals.aje.a119941. [DOI] [PubMed] [Google Scholar]
  3. CLARKE S. K., CORNER B. D., GAMBIER D. M., MACRAE J., PEACOCK D. B. VIRUSES ASSOCIATED WITH ACUTE RESPIRATORY INFECTIONS. Br Med J. 1964 Jun 13;1(5397):1536–1539. doi: 10.1136/bmj.1.5397.1536. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GRAYSTON J. T., JOHNSTON P. B., LOOSLI C. G., SMITH M. E. An improved technique for the neutralization test with adenoviruses in HeLa cell cultures. J Infect Dis. 1956 Sep-Oct;99(2):188–198. doi: 10.1093/infdis/99.2.188. [DOI] [PubMed] [Google Scholar]
  5. KAWAI K. Pathology and pathologic anatomy of adenovirus infection. Based on three autopsy cases of infantile pneumonia. Jpn J Exp Med. 1959 Aug;29:359–368. [PubMed] [Google Scholar]
  6. MACFARLANE P. S., SOMMERVILLE R. G. Non-tuberculous juvenile bronchiectasis: a virus disease? Lancet. 1957 Apr 13;272(6972):770–771. doi: 10.1016/s0140-6736(57)91031-0. [DOI] [PubMed] [Google Scholar]
  7. MAISEL J. C., PIERCE W. E., CRAWFORD Y. E., ROSENBAUM M. J. Virus pneumonia and adenovirus infection: a reappraisal. Am J Hyg. 1962 Jan;75:56–68. doi: 10.1093/oxfordjournals.aje.a120234. [DOI] [PubMed] [Google Scholar]
  8. RYTEL M. W., CONNER G. H., WELCH C. C., KRAYBILL W. H., EDWARDS E. A., ROSENBAUM M. J., FRANK P. F., MILLER L. F. INFECTIOUS AGENTS ASSOCIATED WITH CYLINDRICAL BRONCHIECTASIS. Dis Chest. 1964 Jul;46:23–28. doi: 10.1378/chest.46.1.23. [DOI] [PubMed] [Google Scholar]
  9. VAN DER VEEN J., DIJKMAN J. H. Association of type 21 adenovirus with acute respiratory illness in military recruits. Am J Hyg. 1962 Sep;76:149–159. doi: 10.1093/oxfordjournals.aje.a120270. [DOI] [PubMed] [Google Scholar]
  10. WRIGHT H. T., Jr, BECKWITH J. B., GWINN J. L. A FATAL CASE OF INCLUSION BODY PNEUMONIA IN AN INFANT INFECTED WITH ADENOVIRUS TYPE 3. J Pediatr. 1964 Apr;64:528–533. doi: 10.1016/s0022-3476(64)80342-5. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES