Abstract
Three juvenile diabetics in partial remission were studied before and after the recurrence of overt diabetes. The remissions were partial because glucose tolerance never returned to normal. However, it improved sufficiently to cause the discontinuance of insulin therapy for at least four months.
The insulin output in response to double glucose tolerance tests was increased during remission. The degree of remission seemed to be related to the magnitude of the insulin response to glucose. In two of the patients the increase was low and the response very slight. The third patient, however, had a delayed hyper-response and his carbohydrate tolerance during the remission was much more improved than those of the other patients.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baker L., Kaye R., Root A. W. The early partial remission of juvenile diabetes mellitus. The roles of insulin and growth hormone. J Pediatr. 1967 Dec;71(6):825–831. doi: 10.1016/s0022-3476(67)80007-6. [DOI] [PubMed] [Google Scholar]
- Carlström S., Ingemanson C. A. Juvenile diabetes with long-standing remission. A case report. Diabetologia. 1967 Oct;3(5):465–467. doi: 10.1007/BF01228084. [DOI] [PubMed] [Google Scholar]
- Christensen N. J. Notes on the glucose oxidase method. Scand J Clin Lab Invest. 1967;19(4):379–384. doi: 10.3109/00365516709090653. [DOI] [PubMed] [Google Scholar]
- GRODSKY G. M., KARAM J. H., PAVLATOS F. C., FORSHAM P. H. SERUM-INSULIN RESPONSE TO GLUCOSE IN PREDIABETIC SUBJECTS. Lancet. 1965 Feb 6;1(7380):290–291. doi: 10.1016/s0140-6736(65)91027-5. [DOI] [PubMed] [Google Scholar]
- Hernandez A., Zorrilla E., Gershberg H. Serum insulin in remission of juvenile diabetes. Lancet. 1968 Jul 27;2(7561):223–223. doi: 10.1016/s0140-6736(68)92662-7. [DOI] [PubMed] [Google Scholar]
- Johansen K., Lundbaek K. Plasma-insulin in mild juvenile diabetes. Lancet. 1967 Jun 10;1(7502):1257–1259. doi: 10.1016/s0140-6736(67)92719-5. [DOI] [PubMed] [Google Scholar]