Abstract
A man presented with the sudden onset of pernicious anaemia at the age of 21. He had been treated for hypothyroidism since the age of 6. His father and only paternal aunt were also found to have pernicious anaemia. Gastric and thyroid antibody studies showed one or more antibodies to be present in all three subjects, as well as in the patient's mother.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ARDEMAN S., CHANARIN I. A METHOD FOR THE ASSAY OF HUMAN GASTRIC INTRINSIC FACTOR AND FOR THE DETECTION AND TITRATION OF ANTIBODIES AGAINST INTRINSIC FACTOR. Lancet. 1963 Dec 28;2(7322):1350–1354. doi: 10.1016/s0140-6736(63)90736-0. [DOI] [PubMed] [Google Scholar]
- Doniach D., Roitt I. M., Taylor K. B. Autoimmunity in pernicious anemia and thyroiditis: a family study. Ann N Y Acad Sci. 1965 Jun 30;124(2):605–625. doi: 10.1111/j.1749-6632.1965.tb18990.x. [DOI] [PubMed] [Google Scholar]
- Doniach D., Roitt I. M. The significance of gastric antibodies. Family studies on gastric autoimmunity. Proc R Soc Med. 1966 Aug;59(8):691–694. doi: 10.1177/003591576605900803. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mohamed S. D., McKay E., Galloway W. H. Juvenile familial megaloblastic anaemia due to selective malabsorption of vitamin B-12. A family study and a review of the literature. Q J Med. 1966 Jul;35(139):433–453. [PubMed] [Google Scholar]
