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British Medical Journal logoLink to British Medical Journal
. 1969 May 3;2(5652):279–280. doi: 10.1136/bmj.2.5652.279

Effect of Propranolol on Exercise Tolerance of Patients with Atrial Fibrillation

R W Brown, A J Goble
PMCID: PMC1983196  PMID: 4888876

Abstract

Six patients with atrial fibrillation who were taking digitalis were exercised before and after 30 mg. of propranolol twice daily. Though there was a lower pulse rate at rest and on exercise in all patients, three suffered deterioration of exercise tolerance. It is concluded that propranolol does not improve the exercise tolerance of patients with atrial fibrillation whose resting ventricular rate is controlled with digitalis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Conway N., Seymour J., Gelson A. Cardiac failure in patients with valvar heart disease after use of propranolol to control atrial fibrillation. Br Med J. 1968 Apr 27;2(5599):213–214. doi: 10.1136/bmj.2.5599.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Epstein S. E., Braunwald E. Beta-adrenergic receptor blocking drugs. Mechanisms of action and clinical applications. N Engl J Med. 1966 Nov 24;275(21):1175–concl. doi: 10.1056/NEJM196611242752108. [DOI] [PubMed] [Google Scholar]
  3. HARRISON D. C., GRIFFIN J. R., FIENE T. J. EFFECTS OF BETA-ADRENERGIC BLOCKADE WITH PROPRANOLOL IN PATIENTS WITH ATRIAL ARRHYTHMIAS. N Engl J Med. 1965 Aug 19;273:410–415. doi: 10.1056/NEJM196508192730802. [DOI] [PubMed] [Google Scholar]
  4. Hornsten T. R., Bruce R. A. Effects of atrial fibrillation on exercise performance in patients with cardiac disease. Circulation. 1968 Apr;37(4):543–548. doi: 10.1161/01.cir.37.4.543. [DOI] [PubMed] [Google Scholar]
  5. ROWLANDS D. J., HOWITT G., MARKMAN P. PROPRANOLOL (INDERAL) IN DISTURBANCES OF CARDIAC RHYTHM. Br Med J. 1965 Apr 3;1(5439):891–894. doi: 10.1136/bmj.1.5439.891. [DOI] [PMC free article] [PubMed] [Google Scholar]

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