Abstract
Possible diurnal variation in the blood sugar response to oral glucose was studied by comparing, in the same individuals, the results of oral glucose tolerance tests performed in the morning and the afternoon. In a group of normal individuals the blood sugar levels were significantly higher in the afternoon. In hyperglycaemic individuals the diurnal variation decreased as the blood sugar levels reached during the morning test increased, so that in a group of grossly hyperglycaemic men the mean morning and afternoon tests were almost identical. The causes of this diurnal variation are not known.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bowen A. J., Reeves R. L. Diurnal variation in glucose tolerance. Arch Intern Med. 1967 Mar;119(3):261–264. [PubMed] [Google Scholar]
- DOE R. P., FLINK E. B., GOODSELL M. G. Relationship of diurnal variation in 17-hydroxycorticosteroid levels in blood and urine to eosinophils and electrolyte excretion. J Clin Endocrinol Metab. 1956 Feb;16(2):196–206. doi: 10.1210/jcem-16-2-196. [DOI] [PubMed] [Google Scholar]
- Freinkel N., Mager M., Vinnick L. Cyclicity in the interrelationships between plasma insulin and glucose during starvation in normal young men. J Lab Clin Med. 1968 Jan;71(1):171–178. [PubMed] [Google Scholar]
- HAYNER N. S., KJELSBERG M. O., EPSTEIN F. H., FRANCIS T., Jr CARBOHYDRATE TOLERANCE AND DIABETES IN A TOTAL COMMUNITY, TECUMSEH, MICHIGAN. 1. EFFECTS OF AGE, SEX, AND TEST CONDITIONS ON ONE-HOUR GLUCOSE TOLERANCE IN ADULTS. Diabetes. 1965 Jul;14:413–423. doi: 10.2337/diab.14.7.413. [DOI] [PubMed] [Google Scholar]
- Siperstein M. D., Norton W., Unger R. H., Madison L. L. Muscle capillary basement membrane width in normal, diabetic and prediabetic patients. Trans Assoc Am Physicians. 1966;79:330–347. [PubMed] [Google Scholar]
- Whichelow M. J., Wigglesworth A., Cox B. D., Butterfield W. J., Abrams M. E. Critical analysis of blood sugar measurements in diabetes detection and diagnosis. Diabetes. 1967 Apr;16(4):219–226. doi: 10.2337/diab.16.4.219. [DOI] [PubMed] [Google Scholar]