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. 1969 May 17;2(5654):422–423. doi: 10.1136/bmj.2.5654.422

Effect of Tetrabenazine on Extrapyramidal Movement Disorders

M A Dalby
PMCID: PMC1983347  PMID: 4238453

Abstract

Thirty patients with various extrapyramidal movement disorders were treated for prolonged periods with 75 to 225 mg. daily of tetrabenazine. In patients with choreiform and hemiballistic motor activity the involuntary movements were diminished or abolished. In patients with cerebellar or Parkinsonian tremor the tremor was aggravated in moderately severe cases, but was uninfluenced in severe cases. In all cases the dyskinesia returned when- the drug was stopped.

Side-effects were inconsiderable and disappeared on reducing the dose slightly. Hence the drug may be an important alternative to neurosurgical treatment of hyperkinesias and especially suitable for severely disabled patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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