Skip to main content
British Medical Journal logoLink to British Medical Journal
letter
. 1969 May 24;2(5655):490. doi: 10.1136/bmj.2.5655.490

Insulin Secretion in Cardiogenic Shock

J R W Dykes, C Saxton, S H Taylor
PMCID: PMC1983439  PMID: 5771581

Abstract

A nearly complete suppression of insulin secretion was observed in four patients in circulatory shock following acute myocardial infarction. This may be due to intense sympathetic activity and raised catecholamine excretion associated with shock.

Full text

PDF

Page 490

490

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allison S. P., Hinton P., Chamberlain M. J. Intravenous glucose-tolerance, insulin, and free-fatty-acid levels in burned patients. Lancet. 1968 Nov 23;2(7578):1113–1116. doi: 10.1016/s0140-6736(68)91581-x. [DOI] [PubMed] [Google Scholar]
  2. Allison S. P., Prowse K., Chamberlain M. J. Failure of insulin response to glucose load during operation and after myocardial infarction. Lancet. 1967 Mar 4;1(7488):478–481. doi: 10.1016/s0140-6736(67)91097-5. [DOI] [PubMed] [Google Scholar]
  3. HALES C. N., RANDLE P. J. Immunoassay of insulin with insulin-antibody precipitate. Biochem J. 1963 Jul;88:137–146. doi: 10.1042/bj0880137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. MACKENZIE G. J., FLENLEY D. C., TAYLOR S. H., MCDONALD A. H., STAUNTON H. P., DONALD K. W. CIRCULATORY AND RESPIRATORY STUDIES IN MYOCARDIAL INFARCTION AND CARDIOGENIC SHOCK. Lancet. 1964 Oct 17;2(7364):825–832. doi: 10.1016/s0140-6736(64)90684-1. [DOI] [PubMed] [Google Scholar]
  5. Porte D., Jr, Graber A. L., Kuzuya T., Williams R. H. The effect of epinephrine on immunoreactive insulin levels in man. J Clin Invest. 1966 Feb;45(2):228–236. doi: 10.1172/JCI105335. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. SELTZER H. S. Quantitative effects of glucose, sulfonylureas, salicylate, and indole-3-acetic acid on the secretion of insulin activity into pancreatic venous blood. J Clin Invest. 1962 Feb;41:289–300. doi: 10.1172/JCI104482. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Valori C., Thomas M., Shillingford J. P. Urinary excretion of free noradrenaline and adrenaline following acute myocardial infarction. Lancet. 1967 Jan 21;1(7482):127–130. doi: 10.1016/s0140-6736(67)91033-1. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES