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. 1969 May 31;2(5656):547–550. doi: 10.1136/bmj.2.5656.547

Acidaemia and Salicylate Poisoning in Adults

A T Proudfoot, S S Brown
PMCID: PMC1983473  PMID: 5769889

Abstract

A review of the arterial acid-base status on admission to hospital of 62 adults with severe salicylate poisoning showed that arterial pH was normal or high in most patients, but low in 8. The mean plasma salicylate concentrations of the acidaemic and nonacidaemic patients were similar and the difference in arterial pH was associated with a marked fall in standard bicarbonate in the former group. No significant difference of Pco2 between the two groups was found, and hence no simple relationship exists between hypocapnia and the development of acidaemia in salicylate poisoning. Acidaemia is shown to be associated with impaired consciousness and to carry a grave prognosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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