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. 1969 May 31;2(5656):533–535. doi: 10.1136/bmj.2.5656.533

Nephrotic Syndrome Due to Primary Renal Disease in Adults: I. Survey of Incidence in South-east England

P Sharpstone, C S Ogg, J S Cameron
PMCID: PMC1983477  PMID: 5769886

Abstract

In a prospective survey of the nephritic syndrome due to primary renal disease in adult patients in the South-east Metropolitan Region of England 50 patients were seen in a two-year period—a minimum annual incidence of 9·0 new cases per million adult population. The frequency distribution of the three main histological groups was “minimal change” 30%, membranous nephropathy 12%, and proliferative glomerulonephritis 58%. The higher proportion of patients with minimal histological change compared with that found in most previously published series may be explained by the avoidance of selection of patients for inclusion. The much lower incidence of membranous nephropathy probably reflects the use of stricter histological criteria for this diagnosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARNEIL G. C. 164 children with nephrosis. Lancet. 1961 Nov 18;2(7212):1103–1110. doi: 10.1016/s0140-6736(61)91026-1. [DOI] [PubMed] [Google Scholar]
  2. BERGER J., de MONTERA, GALLE P. [Study of 100 renal biopsies of the nephrotic syndrome]. Arch Anat Pathol (Paris) 1961 Dec;9:313–322. [PubMed] [Google Scholar]
  3. BERMAN L. B., SCHREINER G. E. Clinical and histologic spectrum of the nephrotic syndrome. Am J Med. 1958 Feb;24(2):249–267. doi: 10.1016/0002-9343(58)90314-0. [DOI] [PubMed] [Google Scholar]
  4. BLAINEY J. D., BREWER D. B., HARDWICKE J., SOOTHILL J. F. The nephrotic syndrome. Diagnosis by renal biopsy and biochemical and immunological analyses related to the response to steroid therapy. Q J Med. 1960 Apr;29:235–256. [PubMed] [Google Scholar]
  5. Brandt K., Cathcart E. S., Cohen A. S. A clinical analysis of the course and prognosis of forty-two patients with amyloidosis. Am J Med. 1968 Jun;44(6):955–969. doi: 10.1016/0002-9343(68)90095-8. [DOI] [PubMed] [Google Scholar]
  6. Cameron J. S., Blandford G. The simple assessment of selectivity in heavy proteinuria. Lancet. 1966 Jul 30;2(7457):242–247. doi: 10.1016/s0140-6736(66)92539-6. [DOI] [PubMed] [Google Scholar]
  7. Cameron J. S. Histology, protein clearances, and response to treatment in the nephrotic syndrome. Br Med J. 1968 Nov 9;4(5627):352–356. doi: 10.1136/bmj.4.5627.352. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hiller A., McIntosh J. F., Van Slyke D. D. THE EXCRETION OF ALBUMIN AND GLOBULIN IN NEPHRITIS. J Clin Invest. 1927 Jun;4(2):235–251. doi: 10.1172/JCI100121. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. KARK R. M., MUEHRCKE R. C. Biopsy of kidney in prone position. Lancet. 1954 May 22;266(6821):1047–1049. doi: 10.1016/s0140-6736(54)91618-9. [DOI] [PubMed] [Google Scholar]
  10. MAXWELL M. H., ADAMS D. A., GOLDMAN R. CORTICOSTEROID THERAPY OF AMYLOID NEPHROTIC SYNDROME. Ann Intern Med. 1964 Apr;60:539–555. doi: 10.7326/0003-4819-60-4-539. [DOI] [PubMed] [Google Scholar]
  11. MCGOVERN V. J. PERSISTENT NEPHROTIC SYNDROME: A RENAL BIOPSY STUDY. Australas Ann Med. 1964 Nov;13:306–312. doi: 10.1111/imj.1964.13.4.306. [DOI] [PubMed] [Google Scholar]
  12. PEARL M. A., BURCH R. R., CARVAJAL E., MCCRACKEN B. H., WOODY H. B., STERNBERG W. H. NEPHROTIC SYNDROME. A CLINICAL AND PATHOLICAL STUDY. Arch Intern Med. 1963 Nov;112:716–726. doi: 10.1001/archinte.1963.03860050103011. [DOI] [PubMed] [Google Scholar]
  13. ROTHENBERG M. B., HEYMANN W. The incidence of the nephrotic syndrome in children. Pediatrics. 1957 Mar;19(3):446–452. [PubMed] [Google Scholar]

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