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. 1969 Jun 28;2(5660):795–798. doi: 10.1136/bmj.2.5660.795

Blood Platelet Behaviour during and after Open-heart Surgery

F N McKenzie, D P Dhall, K-E Arfors, S Nordlund, N A Matheson
PMCID: PMC1983771  PMID: 5784615

Abstract

In view of the high incidence of thromboembolic complications after the insertion of cardiac valve prostheses, platelet adhesiveness and aggregation was measured in whole blood before, during, and for several days after this operation in 10 patients. Cardiopulmonary bypass resulted in a profound decrease in the platelet count, in the number of adhesive platelets, and in platelet aggregation. These changes returned to near preoperative levels by the sixth postoperative day. Thereafter a consistent and sustained increase in platelet count, in the number of adhesive platelets, and in platelet aggregation was observed. The results suggest that the prevalence of thromboembolism after valve replacement may be due partly to changes in platelet behaviour.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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