Abstract
In 12 subjects with normal glucose tolerance fructose infusion was associated with a rise in plasma insulin and plasma corticoid levels. Similar but lesser changes were seen in seven maturity onset diabetics in whom there was also a considerable rise in blood glucose. It is suggested that a catabolite of fructose is responsible for these changes.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bergström J., Hultman E. Synthesis of muscle glycogen in man after glucose and fructose infusion. Acta Med Scand. 1967 Jul;182(1):93–107. doi: 10.1111/j.0954-6820.1967.tb11503.x. [DOI] [PubMed] [Google Scholar]
- Coore H. G., Randle P. J. Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro. Biochem J. 1964 Oct;93(1):66–78. doi: 10.1042/bj0930066. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elliott W. C., Cohen L. S., Klein M. D., Lane F. J., Gorlin R. Effects of rapid fructose infusion in man. J Appl Physiol. 1967 Dec;23(6):865–869. doi: 10.1152/jappl.1967.23.6.865. [DOI] [PubMed] [Google Scholar]
- GRODSKY G. M., BATTS A. A., BENNETT L. L., VCELLA C., MCWILLIAMS N. B., SMITH D. F. EFFECTS OF CARBOHYDRATES ON SECRETION OF INSULIN FROM ISOLATED RAT PANCREAS. Am J Physiol. 1963 Oct;205:638–644. doi: 10.1152/ajplegacy.1963.205.4.638. [DOI] [PubMed] [Google Scholar]
- Goetz F. C., Maney J. W., Greenberg B. Z. The regulation of insulin secretion: effects of the infusion of glucose, ribose, and other sugars into the portal veins of dogs. J Lab Clin Med. 1967 Apr;69(4):537–557. [PubMed] [Google Scholar]
- HALES C. N., RANDLE P. J. Immunoassay of insulin with insulin-antibody precipitate. Biochem J. 1963 Jul;88:137–146. doi: 10.1042/bj0880137. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KULKA R. G. Colorimetric estimation of ketopentoses and ketohexoses. Biochem J. 1956 Aug;63(4):542–548. doi: 10.1042/bj0630542. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MATTINGLY D. A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma. J Clin Pathol. 1962 Jul;15:374–379. doi: 10.1136/jcp.15.4.374. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SAMOLS E., DORMANDY T. L. Insulin response to fructose and galactose. Lancet. 1963 Mar 2;1(7279):478–479. doi: 10.1016/s0140-6736(63)92367-5. [DOI] [PubMed] [Google Scholar]
- TAGNON R. F., DEVREUX S. Effect of intravenous injection of fructose, with and without ACTH administration, on the level of blood glucose. J Clin Endocrinol Metab. 1955 Dec;15(12):1475–1481. doi: 10.1210/jcem-15-12-1475. [DOI] [PubMed] [Google Scholar]
- WEINSTEIN J. J., ROE J. H. The utilization of fructose by human subjects and animals. J Lab Clin Med. 1952 Jul;40(1):39–47. [PubMed] [Google Scholar]