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. 1968 Aug 3;3(5613):285–287. doi: 10.1136/bmj.3.5613.285

Resistance to Suppression by Dexamethasone of Plasma 11-O.H.C.S. Levels in Severe Depressive Illness

B J Carroll, F I R Martin, Brian Davies
PMCID: PMC1986248  PMID: 4385601

Abstract

Use of the midnight dexamethasone suppression test showed that the plasma 11-hydroxycorticosteroid (11-O.H.C.S.) level did not undergo its normal reduction in 14 out of 27 patients with severe depression. Resistance to dexamethasone suppression correlated with the clinical rating of the severity of depression, while recovery from depression was associated with return of normal responsiveness to dexamethasone. The explanation of these findings is unknown.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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