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. Author manuscript; available in PMC: 2007 Oct 1.
Published in final edited form as: Vaccine. 2006 Nov 7;25(8):1409–1415. doi: 10.1016/j.vaccine.2006.10.043

Figure 2. DNA minigene vaccines protect mice from challenge with D2F2 breast carcinoma.

Figure 2

Groups of BALB/c mice (n=8) were immunized 3 times at 1 wk intervals with attenuated Salmonella typhimurium RE-88 harboring the vectors indicated. Mice were challenged 2 wk after the last immunization by i.v. injection of 2x105 D2F2 breast carcinoma cells. Upper panel: Schematic of experimental protocol. Lower panel: Survival rate of mice 25 d after tumor cell challenge. The FLK-1 whole gene vaccine was used as positive control.