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. 1990 Apr;71(2):295–303.

Role of immunity to mycobacterial stress proteins in rheumatoid arthritis.

L McLean 1, V Winrow 1, D Blake 1
PMCID: PMC1998702  PMID: 2184873

Abstract

'Stress Proteins in Inflammation' provided a forum for the discussion of topical issues in this rapidly moving field. The mycobacterial 65 kDa stress proteins play a key role in certain animal models of inflammatory arthritis. However, the impression emerging is that the mechanism probably involves more than a simple cross-reaction between mycobacterial SP65 and either the host SP65 or a cartilage antigen, and that evidence for a primary role in human rheumatoid arthritis is lacking. A realistic role for immune responses against stress proteins might be the amplification or perpetuation of inflammation. If so, this is unlikely to be limited to arthritis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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