Skip to main content
British Journal of Cancer logoLink to British Journal of Cancer
. 1986 Aug;54(2):337–339. doi: 10.1038/bjc.1986.182

Site-specific antitumour effects of 2 pyrimidinone compounds in rats.

A M Eggermont, R L Marquet, R W De Bruin, W Weimar, J Jeekel
PMCID: PMC2001514  PMID: 3741769

Full text

PDF
337

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gomez J., Pohajdak B., O'Neill S., Wilkins J., Greenberg A. H. Activation of rat and human alveolar macrophage intracellular microbicidal activity by a preformed LGL cytokine. J Immunol. 1985 Aug;135(2):1194–1200. [PubMed] [Google Scholar]
  2. Hanna N., Fidler I. J. Role of natural killer cells in the destruction of circulating tumor emboli. J Natl Cancer Inst. 1980 Oct;65(4):801–809. doi: 10.1093/jnci/65.4.801. [DOI] [PubMed] [Google Scholar]
  3. Kasahara T., Djeu J. Y., Dougherty S. F., Oppenheim J. J. Capacity of human large granular lymphocytes (LGL) to produce multiple lymphokines: interleukin 2, interferon, and colony stimulating factor. J Immunol. 1983 Nov;131(5):2379–2385. [PubMed] [Google Scholar]
  4. Li L. H., Wallace T. L., Richard K. A., Tracey D. E. Mechanism of antitumor action of pyrimidinones in the treatment of B16 melanoma and P388 leukemia. Cancer Res. 1985 Feb;45(2):532–538. [PubMed] [Google Scholar]
  5. Lotzová E., Savary C. A., Khan A., Stringfellow D. A. Stimulation of natural killer cells in two random-bred strains of athymic rats by interferon-inducing pyrimidinone. J Immunol. 1984 May;132(5):2566–2570. [PubMed] [Google Scholar]
  6. Lotzová E., Savary C. A., Stringfellow D. A. 5-halo-6-phenyl pyrimidinones: new molecules with cancer therapeutic potential and interferon-inducing capacity are strong inducers of murine natural killer cells. J Immunol. 1983 Feb;130(2):965–969. [PubMed] [Google Scholar]
  7. Marquet R. L., Schellekens H., Westbroek D. L., Jeekel J. Effect of treatment with interferon and cyclophosphamide on the growth of a spontaneous liposarcoma in rats. Int J Cancer. 1983 Feb 15;31(2):223–226. doi: 10.1002/ijc.2910310215. [DOI] [PubMed] [Google Scholar]
  8. Milas L., Hersh E. M., Stringfellow D. A., Hunter N. Studies on the antitumor activities of pyrimidinone-interferon inducers. I. Effect against artificial and spontaneous lung metastases of murine tumors. J Natl Cancer Inst. 1982 Jan;68(1):139–145. [PubMed] [Google Scholar]
  9. Oku T., Imanishi J., Kishida T. Interferon counteracts pyrimidinone-induced hyporeactivity and the combined treatment has antitumor effect in mice. Gan. 1984 Jul;75(7):631–640. [PubMed] [Google Scholar]
  10. Ortaldo J. R., Bonnard G. D., Herberman R. B. Cytotoxic reactivity of human lymphocytes cultured in vitro. J Immunol. 1977 Oct;119(4):1351–1357. [PubMed] [Google Scholar]
  11. Stringfellow D. A., Vanderberg H. C., Weed S. D. Interferon induction by 5-halo-6-phenyl pyrimidinones. J Interferon Res. 1980 Fall;1(1):1–14. doi: 10.1089/jir.1980.1.1. [DOI] [PubMed] [Google Scholar]
  12. Talmadge J. E., Herberman R. B., Chirigos M. A., Maluish A. E., Schneider M. A., Adams J. S., Philips H., Thurman G. B., Varesio L., Long C. Hyporesponsiveness to augmentation of murine natural killer cell activity in different anatomical compartments by multiple injections of various immunomodulators including recombinant interferons and interleukin 2. J Immunol. 1985 Oct;135(4):2483–2491. [PubMed] [Google Scholar]
  13. Talmadge J. E., Maluish A. E., Collins M., Schneider M., Herberman R. B., Oldham R. K., Wiltrout R. H. Immunomodulation and antitumor effects of MVE-2 in mice. J Biol Response Mod. 1984 Dec;3(6):634–652. [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES