Abstract
Using Cox's Proportional Hazard Model, we have demonstrated the influence of age, sex, microscopic tumour type, extent of primary tumour, nodal status and the presence of metastases on prognosis, in our population of 441 patients with thyroid carcinoma. The TNM classification contributes significantly to survival, but does not include other contributory prognostic variables, whereas the prognostic index developed by the EORTC thyroid study group, which takes account of age and histology, proved a reliable predictor of survival for our patient group.
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Selected References
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- Beaugié J. M., Brown C. L., Doniach I., Richardson J. E. Primary malignant tumours of the thyroid: the relationship between histological classification and clinical behaviour. Br J Surg. 1976 Mar;63(3):173–181. doi: 10.1002/bjs.1800630303. [DOI] [PubMed] [Google Scholar]
- Bell G. O. Cancer of the thyroid. Med Clin North Am. 1975 Mar;59(2):459–470. doi: 10.1016/s0025-7125(16)32047-8. [DOI] [PubMed] [Google Scholar]
- Byar D. P., Green S. B., Dor P., Williams E. D., Colon J., van Gilse H. A., Mayer M., Sylvester R. J., van Glabbeke M. A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. Thyroid Cancer Cooperative Group. Eur J Cancer. 1979 Aug;15(8):1033–1041. doi: 10.1016/0014-2964(79)90291-3. [DOI] [PubMed] [Google Scholar]
- Cady B., Sedgwick C. E., Meissner W. A., Bookwalter J. R., Romagosa V., Werber J. Changing clinical, pathologic, therapeutic, and survival patterns in differentiated thyroid carcinoma. Ann Surg. 1976 Nov;184(5):541–553. doi: 10.1097/00000658-197611000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Campbell D. J., Sage R. H. Thyroid cancer: twenty years' experience in a general hospital. Br J Surg. 1975 Mar;62(3):207–214. doi: 10.1002/bjs.1800620309. [DOI] [PubMed] [Google Scholar]
- Halnan K. E. Influence of age and sex on incidence and prognosis of thyroid cancer. Three hundred forty-four cases followed for ten years. Cancer. 1966 Nov;19(11):1534–1536. doi: 10.1002/1097-0142(196611)19:11<1534::aid-cncr2820191112>3.0.co;2-3. [DOI] [PubMed] [Google Scholar]
- Staunton M. D., Greening W. P. Treatment of thyroid cancer in 293 patients. Br J Surg. 1976 Apr;63(4):253–258. doi: 10.1002/bjs.1800630402. [DOI] [PubMed] [Google Scholar]