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. 1987 Mar;55(3):321–325. doi: 10.1038/bjc.1987.63

Squamous and adenocarcinoma of the uterine cervix: a comparison using routine data.

P B Silcocks, H Thornton-Jones, M Murphy
PMCID: PMC2001756  PMID: 3567065

Abstract

We studied the clinical, demographic and survival characteristics of more than 5,000 women registered with either squamous or adenocarcinoma of the uterine cervix in South Thames Cancer Registry over the period 1968-81. There were similarities with respect to social class, smoking habit, oestrogen/oral contraceptive use and time trends in incidence but differences between the two cancers were found with respect to age distribution, parity, method of detection and survival. Some of the data are of limited value, having been obtained only from case notes, so the results need some caution in their interpretation. However the results are broadly consistent with those of studies performed in other countries on smaller samples. A methodological issue is also raised, viz. the appropriateness of a disease with well-known characteristics as a comparison group. From our results the likely size of various associations can be judged and used in the design of future studies to clarify the epidemiology of cervical adenocarcinoma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aitken-Swan J., Baird D. Cancer of the uterine cervix in Aberdeenshire. Epidemiological aspects. Br J Cancer. 1966 Dec;20(4):624–641. doi: 10.1038/bjc.1966.75. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BERGSJO P. Adenocarcinoma cervicis uteri. A clinical study. Acta Obstet Gynecol Scand. 1963;42:85–92. doi: 10.3109/00016346309157871. [DOI] [PubMed] [Google Scholar]
  3. BOYD J. T., DOLL R. A STUDY OF THE AETIOLOGY OF CARCINOMA OF THE CERVIX UTERI. Br J Cancer. 1964 Sep;13:419–434. doi: 10.1038/bjc.1964.49. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Buckley J. D., Harris R. W., Doll R., Vessey M. P., Williams P. T. Case-control study of the husbands of women with dysplasia or carcinoma of the cervix uteri. Lancet. 1981 Nov 7;2(8254):1010–1015. doi: 10.1016/s0140-6736(81)91215-0. [DOI] [PubMed] [Google Scholar]
  5. Correa P., Sasano N., Stemmermann G. N., Haenszel W. Pathology of gastric carcinoma in Japanese populations: comparisons between Miyagi prefecture, Japan, and Hawaii. J Natl Cancer Inst. 1973 Nov;51(5):1449–1459. doi: 10.1093/jnci/51.5.1449. [DOI] [PubMed] [Google Scholar]
  6. Henson D., Tarone R. An epidemiologic study of cancer of the cervix, vagina, and vulva based on the Third National Cancer Survey in the United States. Am J Obstet Gynecol. 1977 Nov 1;129(5):525–532. [PubMed] [Google Scholar]
  7. Korhonen M. O. Epidemiological differences between adenocarcinoma and squamous cell carcinoma of the uterine cervix. Gynecol Oncol. 1980 Dec;10(3):312–317. doi: 10.1016/0090-8258(80)90099-2. [DOI] [PubMed] [Google Scholar]
  8. La Vecchia C., Franceschi S., Decarli A., Fasoli M., Gentile A., Tognoni G. Cigarette smoking and the risk of cervical neoplasia. Am J Epidemiol. 1986 Jan;123(1):22–29. doi: 10.1093/oxfordjournals.aje.a114220. [DOI] [PubMed] [Google Scholar]
  9. MacMahon B. Risk factors for endometrial cancer. Gynecol Oncol. 1974 Aug;2(2-3):122–129. doi: 10.1016/0090-8258(74)90003-1. [DOI] [PubMed] [Google Scholar]
  10. Management of advanced ovarian cancer. Lancet. 1980 Nov 8;2(8202):1010–1011. [PubMed] [Google Scholar]
  11. Menczer J., Modan B., Oelsner G., Sharon Z., Steintiz R., Sampson S. Adenocarcinoma of the uterine cervix in Jewish women: a distinct epidemiological entity. Cancer. 1978 Jun;41(6):2464–2467. doi: 10.1002/1097-0142(197806)41:6<2464::aid-cncr2820410655>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
  12. Menczer J., Yaron-Schiffer O., Leventon-Kriss S., Modan M., Modan B. Herpesvirus type 2 in adenocarcinoma of the uterine cervix: a possible association. Cancer. 1981 Oct 1;48(7):1497–1499. doi: 10.1002/1097-0142(19811001)48:7<1497::aid-cncr2820480702>3.0.co;2-i. [DOI] [PubMed] [Google Scholar]
  13. Milsom I., Friberg L. G. Primary adenocarcinoma of the uterine cervix. A clinical study. Cancer. 1983 Sep 1;52(5):942–947. doi: 10.1002/1097-0142(19830901)52:5<942::aid-cncr2820520534>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
  14. Peters R. K., Chao A., Mack T. M., Thomas D., Bernstein L., Henderson B. E. Increased frequency of adenocarcinoma of the uterine cervix in young women in Los Angeles County. J Natl Cancer Inst. 1986 Mar;76(3):423–428. [PubMed] [Google Scholar]
  15. ROTKIN I. D., KING R. W. Environmental variables related to cervical cancer. Am J Obstet Gynecol. 1962 Mar 15;83:720–728. doi: 10.1016/0002-9378(62)90693-2. [DOI] [PubMed] [Google Scholar]
  16. Stellman S. D., Austin H., Wynder E. L. Cervix cancer and cigarette smoking: a case-control study. Am J Epidemiol. 1980 Apr;111(4):383–388. doi: 10.1093/oxfordjournals.aje.a112912. [DOI] [PubMed] [Google Scholar]
  17. Tasker J. T., Collins J. A. Adenocarcinoma of the uterine cervix. Am J Obstet Gynecol. 1974 Feb 1;118(3):344–348. doi: 10.1016/s0002-9378(16)33790-5. [DOI] [PubMed] [Google Scholar]
  18. Wigle D. T., Mao Y., Grace M. Re: "Smoking and cancer of the uterine cervix: hypothesis". Am J Epidemiol. 1980 Jan;111(1):125–127. doi: 10.1093/oxfordjournals.aje.a112862. [DOI] [PubMed] [Google Scholar]
  19. Wilkie N. M., Eglin R. P., Sanders P. G., Clements J. B. The association of herpes simplex virus with squamous carcinoma of the cervix, and studies of the virus thymidine kinase gene. Proc R Soc Lond B Biol Sci. 1980 Nov 19;210(1180):411–421. doi: 10.1098/rspb.1980.0143. [DOI] [PubMed] [Google Scholar]
  20. Williams R. R., Horm J. W. Association of cancer sites with tobacco and alcohol consumption and socioeconomic status of patients: interview study from the Third National Cancer Survey. J Natl Cancer Inst. 1977 Mar;58(3):525–547. doi: 10.1093/jnci/58.3.525. [DOI] [PubMed] [Google Scholar]
  21. Wright N. H., Vessey M. P., Kenward B., McPherson K., Doll R. Neoplasia and dysplasia of the cervix uteri and contraception: a possible protective effect of the diaphragm. Br J Cancer. 1978 Aug;38(2):273–279. doi: 10.1038/bjc.1978.198. [DOI] [PMC free article] [PubMed] [Google Scholar]

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