Skip to main content
British Journal of Cancer logoLink to British Journal of Cancer
. 1972 Feb;26(1):10–14. doi: 10.1038/bjc.1972.4

Cytoplasmic Immunofluorescence of Blood Cells from Myeloma, Hodgkin's Disease and Lymphosarcoma Cases

R O Bankole, H A Bates, W R Swaim, D S Amatuzio
PMCID: PMC2008331  PMID: 4552373

Abstract

The immunofluorescent reaction of peripheral blood cells from 10 multiple myeloma, 10 Hodgkin's and 11 lymphosarcoma cases with antiviral (Rauscher) murine leukaemia (AMR) and antihuman stem cell leukaemia plasma (AHS) antisera was studied. Cells from 25 of these patients were reactive at least once with AMR and AHS or AHS alone. Absorption studies suggested that this cytoplasmic immunofluorescent reaction involved cellular isoantigens. Serial studies on multiple myeloma, Hodgkin's and lymphosarcoma cases with significant fluorescence, showed that the fluorescent cell count variation was correlated with the presence of active disease.

Full text

PDF
10

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bohlool B. B., Schmidt E. L. Nonspecific staining: its control in immunofluorescence examination of soil. Science. 1968 Nov 29;162(3857):1012–1014. doi: 10.1126/science.162.3857.1012. [DOI] [PubMed] [Google Scholar]
  2. FINK M. A., MALMGREN R. A., RAUSCHER F. J., ORR H. C., KARON M. APPLICATION OF IMMUNOFLUORESCENCE TO THE STUDY OF HUMAN LEUKEMIA. J Natl Cancer Inst. 1964 Sep;33:581–588. [PubMed] [Google Scholar]
  3. Fink M. A., Karon M., Rauscher F. J., Malmgren R. A., Orr H. C. Further observations on the immunofluorescence of cells in human leukemia. Cancer. 1965 Oct;18(10):1317–1321. doi: 10.1002/1097-0142(196510)18:10<1317::aid-cncr2820181018>3.0.co;2-x. [DOI] [PubMed] [Google Scholar]
  4. Ioannides A. K., Rosner F., Brenner M., Lee S. L. Immunofluorescent studies of human leukemic cells with antiserum to a murine leukemic virus (Rauscher strain). Blood. 1968 Mar;31(3):381–387. [PubMed] [Google Scholar]
  5. Peacocke I., Amos B., Laszlo J. The detection of iso-antigens on leukemic cells using the cytotoxicity test. Blood. 1966 Nov;28(5):665–673. [PubMed] [Google Scholar]
  6. Swaim W. R., Windschitl H. E., Doscherholmen A., Bankole R. O., Bates H. A. Chronic myelogenous leukemia in Hodgkin's disease: immunofluorescence of cells. Cancer. 1971 Mar;27(3):569–573. doi: 10.1002/1097-0142(197103)27:3<569::aid-cncr2820270309>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES