Skip to main content
British Journal of Cancer logoLink to British Journal of Cancer
. 1968 Dec;22(4):787–797. doi: 10.1038/bjc.1968.93

Enhancement and inhibition of the induction by 7,12-dimethylbenz(a)anthracene of mammary tumours in female Sprague-Dawley rats.

D N Wheatley
PMCID: PMC2008355  PMID: 5705143

Full text

PDF
787

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boyland E., Sims P., Huggins C. Induction of adrenal damage and cancer with metabolites of 7,12-dimethylbenz(a)anthracene. Nature. 1965 Aug 21;207(999):816–817. doi: 10.1038/207816b0. [DOI] [PubMed] [Google Scholar]
  2. Boyland E., Sims P. The effect of pretreatment with adrenal-protecting compounds on the metabolism of 7,12-dimethylbenz[a]anthracene and related compounds by rat-liver homogenates. Biochem J. 1967 Aug;104(2):394–403. doi: 10.1042/bj1040394. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. COOK L., TONER J. J., FELLOWS E. J. The effect of beta-diethylaminoethyl-diphenylpropylacetate hydrochloride (SKF No. 525-A) on hexobarbital. J Pharmacol Exp Ther. 1954 Jun;111(2):131–141. [PubMed] [Google Scholar]
  4. COOPER J. R., BRODIE B. B. The enzymatic metabolism of hexobarbital (evipal). J Pharmacol Exp Ther. 1955 Aug;114(4):409–417. [PubMed] [Google Scholar]
  5. Dao T. L., Varela R. M. On the mechanism of inducing protection of the adrenal cortex against injury from 7,12-dimethylbenz(a)anthracene. I. Effects of inducers on benzpyrene hydroxylase activity. Cancer Res. 1966 May;26(5):1015–1021. [PubMed] [Google Scholar]
  6. HUGGINS C., FUKUNISHI R. INDUCED PROTECTION OF ADRENAL CORTEX AGAINST 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE. INFLUENCE OF ETHIONINE. INDUCTION OF MENADIONE REDUCTASE. INCORPORATION OF THYMIDINE-H3. J Exp Med. 1964 Jan 1;119:923–942. doi: 10.1084/jem.119.6.923. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HUGGINS C., GRAND L. C., BRILLANTES F. P. Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression. Nature. 1961 Jan 21;189:204–207. doi: 10.1038/189204a0. [DOI] [PubMed] [Google Scholar]
  8. HUGGINS C., GRAND L., FUKUNISHI R. AROMATIC INFLUENCES ON THE YIELDS OF MAMMARY CANCERS FOLLOWING ADMINISTRATION OF 7,12-DIMETHYLBENZ(A)ANTHRACENE. Proc Natl Acad Sci U S A. 1964 May;51:737–742. doi: 10.1073/pnas.51.5.737. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. HUGGINS C., MORII S., GRAND L. C. Mammary cancer induced by a single dose of polynuclear hydrocarbons: routes of administration. Ann Surg. 1961 Dec;154(6):315–318. doi: 10.1097/00000658-196112000-00042. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kernohan I. R., Inglis M. S., Wheatley D. N. The effect of liver interference on mammary tumour induction by 7,12-dimethylbenz(a)anthracene in Sprague-Dawley rats. Br J Cancer. 1967 Mar;21(1):214–217. doi: 10.1038/bjc.1967.23. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Levin W., Conney A. H. Stimulatory effect of polycyclic hydrocarbons and aromatic azo derivatives on the metabolism of 7,12-dimethylbenz(alpha)anthracene. Cancer Res. 1967 Nov;27(11):1931–1938. [PubMed] [Google Scholar]
  12. MEECHAN R. J., McCAFFERTY D. E., JONES R. S. 3-Methylcholanthrene as an inhibitor of hepatic cancer induced by 3'-methyl-4-dimethylaminoazobenzene in the diet of the rat: a determination of the time relationships. Cancer Res. 1953 Nov;13(11):802–806. [PubMed] [Google Scholar]
  13. MILLER E. C., MILLER J. A., BROWN R. R., MACDONALD J. C. On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2-acetylaminofluorene. Cancer Res. 1958 May;18(4):469–477. [PubMed] [Google Scholar]
  14. RICHARDSON H. L., STIER A. R., BORSOS-NACHTNEBEL E. Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered. Cancer Res. 1952 May;12(5):356–361. [PubMed] [Google Scholar]
  15. ROGERS L. A., FOUTS J. R. SOME OF THE INTERACTIONS OF SKF 525-A WITH HEPATIC MICROSOMES. J Pharmacol Exp Ther. 1964 Dec;146:286–293. [PubMed] [Google Scholar]
  16. STEVENS L., STEVENS E., CURRIE A. R. HISTOLOGICAL STUDIES AND MEASUREMENT OF NUCLEIC ACID SYNTHESIS IN RAT MAMMARY TUMOURS INDUCED BY 9,10-DIMETHYL-1,2-BENZATHRACENE (DMBA). J Pathol Bacteriol. 1965 Apr;89:581–589. doi: 10.1002/path.1700890217. [DOI] [PubMed] [Google Scholar]
  17. WATTENBERG L. W., LEONG J. L. EFFECTS OF PHENOTHIAZINES ON PROTECTIVE SYSTEMS AGAINST POLYCYCLIC HYDROCARBONS. Cancer Res. 1965 Apr;25:365–370. [PubMed] [Google Scholar]
  18. Wattenberg L. W. Chemoprophylaxis of carcinogenesis: a review. Cancer Res. 1966 Jul;26(7):1520–1526. [PubMed] [Google Scholar]
  19. Wheatley D. N., Inglis M. S. Mammary tumours induced in Sprague-Dawley female ats by 7,12-dimethylbenz(a)anthracene and its hydroxymethyl derivatives. Br J Cancer. 1968 Mar;22(1):122–127. doi: 10.1038/bjc.1968.17. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES