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. 1971 Jun;25(2):280–283. doi: 10.1038/bjc.1971.35

Transformation of Mammalian Cells by Crude Histones

A L Latner, E Longstaff
PMCID: PMC2008463  PMID: 5165582

Abstract

A baby hamster kidney cell line (BHK21), maintained in the presence of crude histone preparations for 3 days, has been shown to undergo morphological and behavioural transformations similar in nature to those obtained with viruses and mycoplasmas.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABERCROMBIE M., AMBROSE E. J. The surface properties of cancer cells: a review. Cancer Res. 1962 Jun;22:525–548. [PubMed] [Google Scholar]
  2. Macpherson I., Russell W. Transformations in hamster cells mediated by mycoplasmas. Nature. 1966 Jun 25;210(5043):1343–1345. doi: 10.1038/2101343a0. [DOI] [PubMed] [Google Scholar]
  3. Russell W. C., Laver W. G., Sanderson P. J. Internal components of adenovirus. Nature. 1968 Sep 14;219(5159):1127–1130. doi: 10.1038/2191127a0. [DOI] [PubMed] [Google Scholar]
  4. STOKER M. Characteristics of normal and transformed clones arising from BHK21 cells exposed to polyoma virus. Virology. 1962 Dec;18:649–651. doi: 10.1016/0042-6822(62)90071-5. [DOI] [PubMed] [Google Scholar]
  5. Stevens J. G., Kado-Boll G. J., Haven C. B. Changes in nuclear basic proteins during pseudorabies virus infection. J Virol. 1969 May;3(5):490–497. doi: 10.1128/jvi.3.5.490-497.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Strohl W. A., Rabson A. S., Rouse H. Adenovirus tumorigenesis: role of the viral genome in determining tumor morphology. Science. 1967 Jun 23;156(3782):1631–1633. doi: 10.1126/science.156.3782.1631. [DOI] [PubMed] [Google Scholar]

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