Skip to main content
British Journal of Cancer logoLink to British Journal of Cancer
. 1970 Mar;24(1):37–47. doi: 10.1038/bjc.1970.6

Clinico-Pathological Study of Malignant Lymphoma in Jamaica

A Talerman
PMCID: PMC2008523  PMID: 4913767

Abstract

A clinico-pathological study of malignant lymphoma in Jamaica was undertaken to examine the disease pattern in a predominantly negro population of West African origin. During a 9-year period (1958-66) 260 histologically verified cases of malignant lymphoma were encountered. The distribution of the different histological types was as follows: Hodgkin's disease 50.9%, lymphosarcoma 33%, reticulum cell sarcoma 14.2%, giant follicular lymphoma 1.9%. No cases of Burkitt's tumour were encountered.

This study indicates that malignant lymphoma is not uncommon in Jamaica, and that its distribution pattern is similar to that observed in Europe and North America, except for the paucity of giant follicular lymphoma, and is different from the pattern observed in parts of Africa populated by Negroes, where Burkitt's tumour is the most common type, and where Hodgkin's disease is relatively uncommon. The age and sex incidence was in general similar to other reported series, but the duration of symptoms was short. The majority of patients presented with generalised peripheral lymphadenopathy. Hepatosplenomegaly and anaemia were common on admission. The prognosis was generally poor in comparison with European and North American series due to advanced stage of disease on presentation.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Azzam S. A. High incidence of Hodgkin's disease in children in Lebanon. Cancer Res. 1966 Jun;26(6):1202–1203. [PubMed] [Google Scholar]
  2. BURKITT D., O'CONOR G. T. Malignant lymphoma in African children. I. A clinical syndrome. Cancer. 1961 Mar-Apr;14:258–269. doi: 10.1002/1097-0142(196103/04)14:2<258::aid-cncr2820140206>3.0.co;2-7. [DOI] [PubMed] [Google Scholar]
  3. Bras G., Watler D. C., Ashmeade-Dyer A. The incidence of malignant neoplasms in Jamaica. Br J Cancer. 1965 Dec;19(4):681–694. doi: 10.1038/bjc.1965.82. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GILLIAM A. G. Age, sex, and race selection at death from leukemia and the lymphomas. Blood. 1953 Aug;8(8):693–702. [PubMed] [Google Scholar]
  5. Gall E. A., Mallory T. B. Malignant Lymphoma: A Clinico-Pathologic Survey of 618 Cases. Am J Pathol. 1942 May;18(3):381–429. [PMC free article] [PubMed] [Google Scholar]
  6. HICKS E. B., RAPPAPORT H., WINTER W. J. Follicular lymphoma; a re-evaluation of its position in the scheme of malignant lymphoma, based on a survey of 253 cases. Cancer. 1956 Jul-Aug;9(4):792–821. doi: 10.1002/1097-0142(195607/08)9:4<792::aid-cncr2820090429>3.0.co;2-b. [DOI] [PubMed] [Google Scholar]
  7. HURST D. W., MEYER O. O. Giant follicular lymphoblastoma. Cancer. 1961 Jul-Aug;14:753–778. doi: 10.1002/1097-0142(199007/08)14:4<753::aid-cncr2820140412>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
  8. Linsell C. A. Cancer incidence in Kenya 1957-63. Br J Cancer. 1967 Sep;21(3):465–473. doi: 10.1038/bjc.1967.54. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. O'CONOR G. T. Malignant lymphoma in African children. II. A pathological entity. Cancer. 1961 Mar-Apr;14:270–283. doi: 10.1002/1097-0142(196103/04)14:2<270::aid-cncr2820140207>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
  10. PETERS M. V., MIDDLEMISS K. C. A study of Hodgkin's disease treated by irradiation. Am J Roentgenol Radium Ther Nucl Med. 1958 Jan;79(1):114–121. [PubMed] [Google Scholar]
  11. PITCOCK J. A., BAUER W. C., McGAVRAN M. H. Hodgkin's disease in children. A clinicopathological study of 46 cases. Cancer. 1959 Sep-Oct;12:1043–1051. doi: 10.1002/1097-0142(195909/10)12:5<1043::aid-cncr2820120525>3.0.co;2-2. [DOI] [PubMed] [Google Scholar]
  12. Smithers D. W. Hodgkin's disease. II. Br Med J. 1967 May 6;2(5548):337–341. doi: 10.1136/bmj.2.5548.337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Solidoro A., Guzmán C., Chang A. Relative increased incidence of childhood Hodgkin's disease in Peru. Cancer Res. 1966 Jun;26(6):1204–1208. [PubMed] [Google Scholar]
  14. Ultmann J. E., Cunningham J. K., Gellhorn A. The clinical picture of Hodgkin's disease. Cancer Res. 1966 Jun;26(6):1047–1062. [PubMed] [Google Scholar]
  15. Wright D. H., Roberts M. The geographical distribution of Burkitt's tumour compared with the geographical distribution of other types of malignant lymphoma in Uganda. Br J Cancer. 1966 Sep;20(3):469–474. doi: 10.1038/bjc.1966.57. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES