Abstract
Total, acid-soluble and protein-bound -SH values have been determined in 88 specimens derived from human malignant tumours and non-malignant tissues, together with the corresponding -SH values in tissues from 19 human foetuses obtained at therapeutic abortion. There appears to be a relationship between acid-soluble -SH and protein -SH in carcinomas of the rectum and colon, but not in any other tissues. In the foetuses, -SH values appear to increase with increasing age, to reach a maximum at about mid-term, then level off.
Full text
PDF






Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- CALCUTT G., CONNORS T. A. TUMOUR SULPHYDRYL LEVELS AND SENSITIVITY TO THE NITROGEN MUSTARD MEROPHAN. Biochem Pharmacol. 1963 Aug;12:839–845. doi: 10.1016/0006-2952(63)90114-x. [DOI] [PubMed] [Google Scholar]
- CALCUTT G., DOXEY D., COATES J. The effects of some chemical carcinogens upon the-SH levels of target and non-target tissues. Br J Cancer. 1960 Dec;14:746–757. doi: 10.1038/bjc.1960.85. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Calcutt G. The effects of some cancer chemotherapy agents on the sulphydryl levels of normal rat tissues. Br J Cancer. 1965 Dec;19(4):883–893. doi: 10.1038/bjc.1965.103. [DOI] [PMC free article] [PubMed] [Google Scholar]
