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. 1974 Sep;30(3):215–221. doi: 10.1038/bjc.1974.184

Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract

G Bone, I Lauder
PMCID: PMC2009205  PMID: 4451626

Abstract

The peripheral blood lymphocyte count has been measured in 74 cases of histologically proven carcinoma of the gastrointestinal tract. The count has been correlated with the pathological stage of tumour spread and the patient's delayed hypersensitivity response to 2.4 dinitrochlorobenzene (DNCB). A statistically significant correlation was found between the peripheral blood lymphocyte count and the response to DNCB. There was linear association between the extent of spread of the tumours and the lymphocyte count. Those patients with low peripheral blood lymphocyte counts tended to have more advanced tumours and a poor response to DNCB. The possible causes of this lymphopenia are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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