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British Journal of Cancer logoLink to British Journal of Cancer
. 1975 Jun;31(6):665–678. doi: 10.1038/bjc.1975.114

A spatial and temporal analysis of four cancers in African gold miners from Southern Africa.

J S Harington, N D McGlashan, E Bradshaw, E W Geddes, L R Purves
PMCID: PMC2009483  PMID: 1174444

Abstract

The pattern of cancer in African gold miners over the 8-year period 1964-71, comprising 2,926,461 man-years of employment was studied. Of the 1344 cancers found, primary liver cancer accounted for 52-8%, oesophageal cancer 12-1%, cancer of the respiratory system 5-4% and cancer of the bladder 4-8%. Analysis of the spatial distribution of these four cancers, both on subcontinental and local scale, showed distinct gradients of occurrence between areas of significantly higher and lower incidence than expected. In the case of primary liver cancer in Mozambique and oesophageal cancer in the Transkei, the spatial distribution reflects closely that found in the general resident population of each territory. The crude incidence rate of primary liver cancer in gold miners from Mozambique dropped sharply over the period of the survey.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BURRELL R. J. Oesophageal cancer in the Bantu. S Afr Med J. 1957 Apr 27;31(17):401–409. [PubMed] [Google Scholar]
  2. Geddes E. W., Falkson G. Differential diagnosis of primary malignant hepatoma in 569 Bantu mineworkers. Cancer. 1973 May;31(5):1216–1221. doi: 10.1002/1097-0142(197305)31:5<1216::aid-cncr2820310527>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]
  3. Harington J. S., McGlashan The temporal and spatial distribution of oesophageal cancer among mineworkers in Southern Africa. Br J Cancer. 1973 Jul;28(1):86–86. doi: 10.1038/bjc.1973.109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. McGlashan N. D. The reality of spatial variations of morbidity and mortality. S Afr Med J. 1974 Aug 10;48(38):1621–1624. [PubMed] [Google Scholar]
  5. Prates M. D., Torres F. O. A cancer survey in Lourenço Marques, Portuguese East Africa. J Natl Cancer Inst. 1965 Nov;35(5):729–757. [PubMed] [Google Scholar]
  6. Robertson M. A., Harington J. S., Bradshaw E. The cancer pattern in African gold miners. Br J Cancer. 1971 Sep;25(3):395–402. doi: 10.1038/bjc.1971.50. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Rose E. F., McGlashan N. D. The spatial distribution of oesophageal carcinoma in the Transkei, South Africa. Br J Cancer. 1975 Feb;31(2):197–206. doi: 10.1038/bjc.1975.26. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Rose E. F. The interplay of factors determining a cancer pattern. Prog Exp Tumor Res. 1969;12:95–101. doi: 10.1159/000386032. [DOI] [PubMed] [Google Scholar]
  9. Schonland M., Bradshaw E. Cancer in the natal African and Indian 1964-66. Int J Cancer. 1968 Mar 15;3(2):304–316. doi: 10.1002/ijc.2910030216. [DOI] [PubMed] [Google Scholar]
  10. von Zeynek E. R. Survey of cancer of the oesophagus in relation to other malignant neoplasms. S Afr Med J. 1973 Feb 24;47(8):325–331. [PubMed] [Google Scholar]

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