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. 1978 Jan;37(1):105–108. doi: 10.1038/bjc.1978.15

Effect of route of administration of 5-fluorouracil on its concentration in blood and lymph.

M Thomas
PMCID: PMC2009494  PMID: 619953

Abstract

The concentration of 5-fluorouracil (FU) in thoracic-duct lymph, portal-vein blood and peripheral arterial blood of beagle dogs was greater after administration into the submucosa of the stomach than after the bolus i.v. injection. The concentration of FU in thoracic-duct lymph, portal-vein blood and arterial blood was least following administration into the lumen of the stomach. The total FU recovered over 6 h from thoracic-duct lymph was compared following the three routes of administration and was found to be greatest following injection into the submucosa of stomach.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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