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. 1978 Jul;38(1):24–33. doi: 10.1038/bjc.1978.160

Radiation leukaemogenesis: is virus really necessary?

J F Loutit, P J Ash
PMCID: PMC2009681  PMID: 581177

Abstract

Generalized lymphosarcomatosis (leukaemia) of non-thymic type occurs in mice bearing 90Sr or 239Pu or 226Ra. Tumours passaged from such mice have been tested for tumour-associated transplantation antigens that could provoke a protective immunity which would be expected if such antigens were determined by virus activated by the irradiation. Sub-threshold doses of living syngeneic tumour, large doses of living allogeneic tumour and large doses of killed syngeneic tumour were without protective effect. This suggests that viruses observed electron micrographically in such tumours are passengers and not causative.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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