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British Journal of Cancer logoLink to British Journal of Cancer
. 1978 Sep;38(3):428–430. doi: 10.1038/bjc.1978.224

Measurement of oestradiol receptors by five institutions on common tissue samples.

R J King, D M Barnes, R A Hawkins, R E Leake, P V Maynard, M M Roberts
PMCID: PMC2009740  PMID: 708574

Abstract

The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be explained by differences in thiol-reagent content of assay medium and by the method of homogenization. Recommendations are made on some of the factors involved in the routine assay of receptors in breast tumours.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hawkins R. A., Hill A., Freedman B., Gore S. M., Roberts M. M., Forrest A. P. Reproducibility of measurements of oestrogen-receptor concentration in breast cancer. Br J Cancer. 1977 Sep;36(3):355–361. doi: 10.1038/bjc.1977.200. [DOI] [PMC free article] [PubMed] [Google Scholar]
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