Abstract
The blood, spleen and liver of RFM/Un mice were examined by means of electron spin resonance (ESR) throughout the course of myeloid leukaemia induced by i.v. injection of leukaemic spleen cells. Marked changes in the concentration of iron transferrin and caeruloplasmin were observed in the blood 1 day after injection. As the disease progressed, changes occurred in the concentrations of the ascorbyl radical and of paramagnetic metal complexes in both spleen and liver. These changes are compared with those induced in RF/J mice injected with normal and leukaemic spleen cells from RFM/Un mice.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Boas J. F., Troup G. J. Electron spin resonance and Mössbauer effect studies of ferritin. Biochim Biophys Acta. 1971 Jan 19;229(1):68–74. doi: 10.1016/0005-2795(71)90319-9. [DOI] [PubMed] [Google Scholar]
- Dodd N. J. Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. I. Paramagnetic metal ions. Br J Cancer. 1975 Jul;32(1):108–120. doi: 10.1038/bjc.1975.137. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dodd N. J., Giron-Conland J. M. Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. II. The ascorbyl radical. Br J Cancer. 1975 Oct;32(4):451–455. doi: 10.1038/bjc.1975.246. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dodd N. J., Silcock J. M. Electron spin resonance study of changes during development of solid yoshida tumour. II. Paramagnetic metal ions. Br J Cancer. 1976 Nov;34(5):556–565. doi: 10.1038/bjc.1976.211. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dodd N. J. Some EPR signals in tumour tissue. Br J Cancer. 1973 Sep;28(3):257–262. doi: 10.1038/bjc.1973.145. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Henry Y., Banerjee R. Electron paramagnetic studies of nitric oxide haemoglobin derivatives: isolated subunits and nitric oxide hybrids. J Mol Biol. 1973 Feb 5;73(4):469–482. doi: 10.1016/0022-2836(73)90094-6. [DOI] [PubMed] [Google Scholar]
- Mallard J. R., Kent M. Electron spin resonance in biological tissues. Phys Med Biol. 1969 Jul;14(3):373–396. doi: 10.1088/0031-9155/14/3/201. [DOI] [PubMed] [Google Scholar]
- Peisach J., Oltzik R., Blumberg W. E. The electron paramagnetic resonance of molybdenum in rat liver and in rat liver mitochondria. Biochim Biophys Acta. 1971 Nov 2;253(1):58–63. doi: 10.1016/0005-2728(71)90233-7. [DOI] [PubMed] [Google Scholar]
- Silcock J. M., Dodd N. J. Electron spin resonance study of changes during development of solid Yoshida tumour. I: Ascorbyl radical. Br J Cancer. 1976 Nov;34(5):550–555. doi: 10.1038/bjc.1976.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swartz H. M., Mailer C., Ambegaonkar S., Antholine W. E., McNellis D. R., Schneller S. J. Paramagnetic changes during development of a transplanted AKR-J leukemia in mice as measured by electron spin resonance. Cancer Res. 1973 Nov;33(11):2588–2595. [PubMed] [Google Scholar]
- Woolum J. C., Tiezzi E., Commoner B. Electron spin resonane of iron-nitric oxide complexes with amino acids, peptides and proteins. Biochim Biophys Acta. 1968 Aug 13;160(3):311–320. doi: 10.1016/0005-2795(68)90204-3. [DOI] [PubMed] [Google Scholar]
- van Leeuwen F. X., Zuyderhoudt F. J., van Gelder B. F., van Gool J. Hemosiderin. an EPR study of water-insoluble iron in human and rat liver. Biochim Biophys Acta. 1977 Dec 22;500(2):304–309. doi: 10.1016/0304-4165(77)90022-8. [DOI] [PubMed] [Google Scholar]