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. 1979 Jan;39(1):64–68. doi: 10.1038/bjc.1979.8

Photodynamic effect of haematoporphyrin throughout the cell cycle of the human cell line NHIK 3025 cultivated in vitro.

T Christensen, J Moan, E Wibe, R Oftebro
PMCID: PMC2009795  PMID: 758929

Abstract

Cells from the established cell line NHIK 3025 were synchronized by repeated mitotic selections. Survival of the synchronized cells after treatment with haematoporphyrin and near-UV light was measured by testing the capacity of the cells to form macroscopic colonies. The sensitivity to photodynamic inactivation was small in early G1, late S and G2. The sensitivity increased throughout late G1 and early S to a maximum in mid S. More than a 100-fold variation is found in the survival after 20 min irradiation in the presence of 4 X 10(-4)M haematoporphyrin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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