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. 1981 May;43(5):632–636. doi: 10.1038/bjc.1981.93

Changes in presenting tumour site of Burkitt's lymphoma in Ghana, West Africa, 1965-1978.

R J Biggar, F K Nkrumah, J Neequaye, P H Levine
PMCID: PMC2010672  PMID: 7248148

Abstract

Between 1965 and 1978, 430 cases of Burkitt's lymphoma were evaluated at the Burkitt Tumour Project, Accra, Ghana. During this period a change in the presenting features occurred, in which abdominal disease increased and facial disease decreased. This change was especially apparent in males, in whom the proportion of cases with abdominal disease more than doubled (chi 2 time trend = 25.99, P = 0.00000017) We speculate that the change may be related to possible changes in BL incidence.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Biggar R. J., Henle W., Fleisher G., Böcker J., Lennette E. T., Henle G. Primary Epstein-Barr virus infections in African infants. I. Decline of maternal antibodies and time of infection. Int J Cancer. 1978 Sep 15;22(3):239–243. doi: 10.1002/ijc.2910220304. [DOI] [PubMed] [Google Scholar]
  2. Biggar R. J., Nkrumah F. K. Burkitt's lymphoma in Ghana: urban-rural distribution, time-space clustering and seasonality. Int J Cancer. 1979 Mar 15;23(3):330–336. doi: 10.1002/ijc.2910230310. [DOI] [PubMed] [Google Scholar]
  3. Biggar R. J., Nkrumah F. K., Perkins I. V. Presenting clinical features of Burkitt's lymphoma in Ghana, West Africa. J Trop Pediatr Environ Child Health. 1979 Dec;25(6):157–161. doi: 10.1093/tropej/25.6.157. [DOI] [PubMed] [Google Scholar]
  4. Brown R. E., Wright B. I. Malignancies in African children how do these differ from malignancies in the United States? Clin Pediatr (Phila) 1967 Feb;6(2):106–115. doi: 10.1177/000992286700600207. [DOI] [PubMed] [Google Scholar]
  5. Burkitt D., Wright D. Geographical and tribal distribution of the African lymphoma in Uganda. Br Med J. 1966 Mar 5;1(5487):569–573. doi: 10.1136/bmj.1.5487.569. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Grundy G. W., Creagan E. T., Fraumeni J. F., Jr Non-Hodgkin's lymphoma in childhood: epidemiologic features. J Natl Cancer Inst. 1973 Sep;51(3):767–776. doi: 10.1093/jnci/51.3.767. [DOI] [PubMed] [Google Scholar]
  7. Henle G., Henle W. Observations on childhood infections with the Epstein-Barr virus. J Infect Dis. 1970 Mar;121(3):303–310. doi: 10.1093/infdis/121.3.303. [DOI] [PubMed] [Google Scholar]
  8. Morrow R. H., Jr, Levine P. H., Ziegler J. L., Berard C. Letter: What is Burkitt's lymphoma? Lancet. 1974 Nov 23;2(7891):1268–1269. doi: 10.1016/s0140-6736(74)90788-0. [DOI] [PubMed] [Google Scholar]
  9. Nkrumah F. K., Perkins I. V. Burkitt's lymphoma: a clinical study of 110 patients. Cancer. 1976 Feb;37(2):671–676. doi: 10.1002/1097-0142(197602)37:2<671::aid-cncr2820370210>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
  10. O'Connor G. T. Persistent immunologic stimulation as a factor in oncogenesis, with special reference to Burkitt's tumor. Am J Med. 1970 Mar;48(3):279–285. doi: 10.1016/0002-9343(70)90057-4. [DOI] [PubMed] [Google Scholar]
  11. Siemiatycki J., Brubaker G., Geser A. Space-time clustering of Burkitt's lymphoma in East Africa: analysis of recent data and a new look at old data. Int J Cancer. 1980 Feb 15;25(2):197–203. doi: 10.1002/ijc.2910250206. [DOI] [PubMed] [Google Scholar]
  12. Williams A. O. Tumors of childhood in Ibadan, Nigeria. Cancer. 1975 Aug;36(2):370–378. doi: 10.1002/1097-0142(197508)36:2<370::aid-cncr2820360212>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]

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